Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerations
Oral mycetoma, or fungal ball, is a rare entity typically affecting immunocompromised individuals; its presentation in the oral cavity, particularly the upper lip of healthy hosts, is exceedingly rare. We report a unique instance of upper lip nasolabial mycetoma in a 60-year-old immunocompetent male...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Oral and Maxillofacial Surgery Cases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221454192500015X |
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| author | Kenichi Ogata Michiaki Akashi Shintaro Kawano |
| author_facet | Kenichi Ogata Michiaki Akashi Shintaro Kawano |
| author_sort | Kenichi Ogata |
| collection | DOAJ |
| description | Oral mycetoma, or fungal ball, is a rare entity typically affecting immunocompromised individuals; its presentation in the oral cavity, particularly the upper lip of healthy hosts, is exceedingly rare. We report a unique instance of upper lip nasolabial mycetoma in a 60-year-old immunocompetent male presenting with painless swelling. Initial imaging (magnetic resonance imaging/ultrasonography) revealed a well-defined, fluid-filled nodule, mimicking a benign neoplasm or mucocele. Excisional biopsy and subsequent histopathological examination with Grocott methenamine silver staining definitively diagnosed mycetoma, revealing encapsulated abscesses with filamentous fungal hyphae, suggestive of Aspergillus etiology. This case highlights the diagnostic ambiguity of atypical fungal infections in immunocompetent patients and underscores the necessity to consider fungal etiologies in the differential diagnosis of oral lesions, irrespective of patient immune status. Histopathology remains crucial for definitive diagnosis and appropriate management. Surgical excision with 1-year follow-up proved to be an effective therapeutic modality for localized oral fungal mycetoma in this healthy individual. |
| format | Article |
| id | doaj-art-0ca774eb610542d583f1ea979ee801b4 |
| institution | DOAJ |
| issn | 2214-5419 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral and Maxillofacial Surgery Cases |
| spelling | doaj-art-0ca774eb610542d583f1ea979ee801b42025-08-20T03:12:39ZengElsevierOral and Maxillofacial Surgery Cases2214-54192025-06-0111210040010.1016/j.omsc.2025.100400Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerationsKenichi Ogata0Michiaki Akashi1Shintaro Kawano2Department of Dentistry and Oral Surgery, Karatsu Red Cross Hospital, 2430 Watada Karatsu City, Saga, 847-8588, Japan; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan; Corresponding author. Department of Dentistry and Oral Surgery, Karatsu Red Cross Hospital, 2430 Watada Karatsu City, Saga, 847-8588, Japan.Department of Diagnostic Pathology, Karatsu Red Cross Hospital, 2430 Watada Karatsu City, Saga, 847-8588, JapanSection of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, JapanOral mycetoma, or fungal ball, is a rare entity typically affecting immunocompromised individuals; its presentation in the oral cavity, particularly the upper lip of healthy hosts, is exceedingly rare. We report a unique instance of upper lip nasolabial mycetoma in a 60-year-old immunocompetent male presenting with painless swelling. Initial imaging (magnetic resonance imaging/ultrasonography) revealed a well-defined, fluid-filled nodule, mimicking a benign neoplasm or mucocele. Excisional biopsy and subsequent histopathological examination with Grocott methenamine silver staining definitively diagnosed mycetoma, revealing encapsulated abscesses with filamentous fungal hyphae, suggestive of Aspergillus etiology. This case highlights the diagnostic ambiguity of atypical fungal infections in immunocompetent patients and underscores the necessity to consider fungal etiologies in the differential diagnosis of oral lesions, irrespective of patient immune status. Histopathology remains crucial for definitive diagnosis and appropriate management. Surgical excision with 1-year follow-up proved to be an effective therapeutic modality for localized oral fungal mycetoma in this healthy individual.http://www.sciencedirect.com/science/article/pii/S221454192500015X |
| spellingShingle | Kenichi Ogata Michiaki Akashi Shintaro Kawano Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerations Oral and Maxillofacial Surgery Cases |
| title | Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerations |
| title_full | Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerations |
| title_fullStr | Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerations |
| title_full_unstemmed | Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerations |
| title_short | Oral mycetoma of the upper lip nasolabial region in a healthy host: A case report and minireview of diagnostic and therapeutic considerations |
| title_sort | oral mycetoma of the upper lip nasolabial region in a healthy host a case report and minireview of diagnostic and therapeutic considerations |
| url | http://www.sciencedirect.com/science/article/pii/S221454192500015X |
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