Sensitivity of the skin test with tuberculous allergen in TB/HIV patients

The sensitivity of skin test with tuberculous allergen in TB/HIV patients has need studied (n = 36) depending on the immune deficiency and the character of tuberculous inflammation. The comparison group included patients with HIV infection and no tuberculosis (n = 54). The test results in HIV patien...

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Main Authors: L. V. Poddubnaya, T. N. Chikurova, M. V. Fedorova, O. V. Igonina, V. A. Dorogan’, T. V. Zyryanova
Format: Article
Language:Russian
Published: New Terra Publishing House 2015-11-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/815
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author L. V. Poddubnaya
T. N. Chikurova
M. V. Fedorova
O. V. Igonina
V. A. Dorogan’
T. V. Zyryanova
author_facet L. V. Poddubnaya
T. N. Chikurova
M. V. Fedorova
O. V. Igonina
V. A. Dorogan’
T. V. Zyryanova
author_sort L. V. Poddubnaya
collection DOAJ
description The sensitivity of skin test with tuberculous allergen in TB/HIV patients has need studied (n = 36) depending on the immune deficiency and the character of tuberculous inflammation. The comparison group included patients with HIV infection and no tuberculosis (n = 54). The test results in HIV patients but without tuberculosis and in the patients with the concurrent condition are directly connected to the degree of immune deficiency. In the patients with HIV infection and progressing tuberculosis the negative results of the test are due to secondary anergy. The patients with severe and expressed immune deficiency the negative results do not exclude the activeness of the infection, thus patients with CD4 level up to 350 + cl/mcl and negative results can be referred as a group of high risk of developing tuberculosis.
format Article
id doaj-art-0ca6e79c0b8b4f8c908d02abfdab8b91
institution OA Journals
issn 2075-1230
2542-1506
language Russian
publishDate 2015-11-01
publisher New Terra Publishing House
record_format Article
series Туберкулез и болезни лёгких
spelling doaj-art-0ca6e79c0b8b4f8c908d02abfdab8b912025-08-20T02:15:51ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062015-11-010111621815Sensitivity of the skin test with tuberculous allergen in TB/HIV patientsL. V. Poddubnaya0T. N. Chikurova1M. V. Fedorova2O. V. Igonina3V. A. Dorogan’4T. V. Zyryanova5Novosibirsk State Medical UniversityRegional TB DispensaryNovosibirsk State Medical UniversityNovosibirsk State Medical UniversityRegional TB DispensaryNovosibirsk State Medical UniversityThe sensitivity of skin test with tuberculous allergen in TB/HIV patients has need studied (n = 36) depending on the immune deficiency and the character of tuberculous inflammation. The comparison group included patients with HIV infection and no tuberculosis (n = 54). The test results in HIV patients but without tuberculosis and in the patients with the concurrent condition are directly connected to the degree of immune deficiency. In the patients with HIV infection and progressing tuberculosis the negative results of the test are due to secondary anergy. The patients with severe and expressed immune deficiency the negative results do not exclude the activeness of the infection, thus patients with CD4 level up to 350 + cl/mcl and negative results can be referred as a group of high risk of developing tuberculosis.https://www.tibl-journal.com/jour/article/view/815tuberculosishiv-infectiontuberculous allergendiaskintestactivity of tuberculous infectionimmune deficiency
spellingShingle L. V. Poddubnaya
T. N. Chikurova
M. V. Fedorova
O. V. Igonina
V. A. Dorogan’
T. V. Zyryanova
Sensitivity of the skin test with tuberculous allergen in TB/HIV patients
Туберкулез и болезни лёгких
tuberculosis
hiv-infection
tuberculous allergen
diaskintest
activity of tuberculous infection
immune deficiency
title Sensitivity of the skin test with tuberculous allergen in TB/HIV patients
title_full Sensitivity of the skin test with tuberculous allergen in TB/HIV patients
title_fullStr Sensitivity of the skin test with tuberculous allergen in TB/HIV patients
title_full_unstemmed Sensitivity of the skin test with tuberculous allergen in TB/HIV patients
title_short Sensitivity of the skin test with tuberculous allergen in TB/HIV patients
title_sort sensitivity of the skin test with tuberculous allergen in tb hiv patients
topic tuberculosis
hiv-infection
tuberculous allergen
diaskintest
activity of tuberculous infection
immune deficiency
url https://www.tibl-journal.com/jour/article/view/815
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AT tnchikurova sensitivityoftheskintestwithtuberculousallergenintbhivpatients
AT mvfedorova sensitivityoftheskintestwithtuberculousallergenintbhivpatients
AT ovigonina sensitivityoftheskintestwithtuberculousallergenintbhivpatients
AT vadorogan sensitivityoftheskintestwithtuberculousallergenintbhivpatients
AT tvzyryanova sensitivityoftheskintestwithtuberculousallergenintbhivpatients