Reward System EEG–fMRI-Pattern Neurofeedback for Major Depressive Disorder with Anhedonia: A Multicenter Pilot Study

Reward System EEG–fMRI-Pattern Neurofeedback for Major Depressive Disorder with Anhedonia: A Multicenter Pilot Study

<b>Background/Objectives:</b> Up to 75% of patients with major depressive disorder (MDD) exhibit persistent anhedonia symptoms related to abnormalities in the positive valence system. Cumulative evidence points to brain dysfunction in the reward system (RS), including in the ventral stri...

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Main Authors: Daniela Amital, Raz Gross, Nadav Goldental, Eyal Fruchter, Haya Yaron-Wachtel, Aron Tendler, Yaki Stern, Lisa Deutsch, Jeffrey D. Voigt, Talma Hendler, Tal Harmelech, Neomi Singer, Haggai Sharon
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Brain Sciences
Subjects:
EFP biomarker
neurofeedback
self-neuromodulation
depression
anhedonia
depression treatment
Online Access:https://www.mdpi.com/2076-3425/15/5/476
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