Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling
Liver macrophages play a role in the development of liver fibrosis progression via the regulation of inflammatory signaling. However, the precise mechanisms of macrophages contributing to liver fibrosis progression remain unclear. Using a preclinical model of CCl4-treated mice, we determined the com...
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| Main Authors: | Soo-Jeung Park, Josefina Garcia Diaz, Tina Comlekoglu, Young S. Hahn |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1528382/full |
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