Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection

Neonatal herpes simplex virus (HSV) infection is a life-threatening infection with high morbidity and mortality rates. Neonatal herpes, most commonly due to HSV type 2, is a multi-system disease; however, initial pulmonary presentation is extremely unusual. We describe an infant presenting with prog...

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Main Authors: Franck Kouadio, Gil Klinger
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2019/9594289
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author Franck Kouadio
Gil Klinger
author_facet Franck Kouadio
Gil Klinger
author_sort Franck Kouadio
collection DOAJ
description Neonatal herpes simplex virus (HSV) infection is a life-threatening infection with high morbidity and mortality rates. Neonatal herpes, most commonly due to HSV type 2, is a multi-system disease; however, initial pulmonary presentation is extremely unusual. We describe an infant presenting with progressive respiratory distress, which was the dominant clinical feature of HSV infection during the first days of life. Sepsis work-up and antibiotic treatment were immediately initiated; however, antiviral treatment was not given until the infant’s death. HSV type 1 was isolated in nasopharyngeal and endotracheal aspirates. HSV pneumonia should be considered in a newborn with respiratory deterioration not compatible with common neonatal respiratory diseases.
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series Case Reports in Critical Care
spelling doaj-art-0c85e44f2fe7494db0afa0dff88ce77e2025-02-03T06:10:53ZengWileyCase Reports in Critical Care2090-64202090-64392019-01-01201910.1155/2019/95942899594289Pneumonia, an Unusual Initial Presentation of Neonatal Herpes InfectionFranck Kouadio0Gil Klinger1Neonatal Intensive Care Unit, Schneider Children’s Medical Center of Israel, Petach Tikva, IsraelNeonatal Intensive Care Unit, Schneider Children’s Medical Center of Israel, Petach Tikva, IsraelNeonatal herpes simplex virus (HSV) infection is a life-threatening infection with high morbidity and mortality rates. Neonatal herpes, most commonly due to HSV type 2, is a multi-system disease; however, initial pulmonary presentation is extremely unusual. We describe an infant presenting with progressive respiratory distress, which was the dominant clinical feature of HSV infection during the first days of life. Sepsis work-up and antibiotic treatment were immediately initiated; however, antiviral treatment was not given until the infant’s death. HSV type 1 was isolated in nasopharyngeal and endotracheal aspirates. HSV pneumonia should be considered in a newborn with respiratory deterioration not compatible with common neonatal respiratory diseases.http://dx.doi.org/10.1155/2019/9594289
spellingShingle Franck Kouadio
Gil Klinger
Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection
Case Reports in Critical Care
title Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection
title_full Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection
title_fullStr Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection
title_full_unstemmed Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection
title_short Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection
title_sort pneumonia an unusual initial presentation of neonatal herpes infection
url http://dx.doi.org/10.1155/2019/9594289
work_keys_str_mv AT franckkouadio pneumoniaanunusualinitialpresentationofneonatalherpesinfection
AT gilklinger pneumoniaanunusualinitialpresentationofneonatalherpesinfection