Ixekizumab in the treatment of psoriatic arthritis
Psoriatic arthritis (PsA) is characterized by a combination of musculoskeletal and extra-articular manifestations, such as peripheral arthritis, axial disease, dactylitis, enthesitis, uveitis, inflammatory bowel disease, psoriasis (Ps). Currently, great progress has been made in the study of the pat...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2024-12-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/3654 |
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| _version_ | 1849400866517286912 |
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| author | Yu. L. Korsakova T. V. Korotaeva |
| author_facet | Yu. L. Korsakova T. V. Korotaeva |
| author_sort | Yu. L. Korsakova |
| collection | DOAJ |
| description | Psoriatic arthritis (PsA) is characterized by a combination of musculoskeletal and extra-articular manifestations, such as peripheral arthritis, axial disease, dactylitis, enthesitis, uveitis, inflammatory bowel disease, psoriasis (Ps). Currently, great progress has been made in the study of the pathogenesis of PsA and pharmacotherapy of this disease. The article presents data on the efficacy and safety of the IL-17 inhibitor ixekizumab (IXE). IXE demonstrates high therapeutic efficacy against all clinical manifestations of PsA in most patients, regardless of concomitant methotrexate intake and previous intake of biological disease-modifying antirheumatic drugs, the presence of cardiometabolic comorbidity. This drug delays the progression of destructive processes in the joints. IXE is indicated for patients with Ps of problematic localization: palmar-plantar, anogenital, scalp and nails. |
| format | Article |
| id | doaj-art-0c85797582f44e5b9674044e97b7a91f |
| institution | Kabale University |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2024-12-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-0c85797582f44e5b9674044e97b7a91f2025-08-20T03:37:54ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922024-12-0162659059710.47360/1995-4484-2024-590-5973030Ixekizumab in the treatment of psoriatic arthritisYu. L. Korsakova0T. V. Korotaeva1V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyPsoriatic arthritis (PsA) is characterized by a combination of musculoskeletal and extra-articular manifestations, such as peripheral arthritis, axial disease, dactylitis, enthesitis, uveitis, inflammatory bowel disease, psoriasis (Ps). Currently, great progress has been made in the study of the pathogenesis of PsA and pharmacotherapy of this disease. The article presents data on the efficacy and safety of the IL-17 inhibitor ixekizumab (IXE). IXE demonstrates high therapeutic efficacy against all clinical manifestations of PsA in most patients, regardless of concomitant methotrexate intake and previous intake of biological disease-modifying antirheumatic drugs, the presence of cardiometabolic comorbidity. This drug delays the progression of destructive processes in the joints. IXE is indicated for patients with Ps of problematic localization: palmar-plantar, anogenital, scalp and nails.https://rsp.mediar-press.net/rsp/article/view/3654ixekizumabinterleukin 17 inhibitorpsoriatic arthritispsoriasis |
| spellingShingle | Yu. L. Korsakova T. V. Korotaeva Ixekizumab in the treatment of psoriatic arthritis Научно-практическая ревматология ixekizumab interleukin 17 inhibitor psoriatic arthritis psoriasis |
| title | Ixekizumab in the treatment of psoriatic arthritis |
| title_full | Ixekizumab in the treatment of psoriatic arthritis |
| title_fullStr | Ixekizumab in the treatment of psoriatic arthritis |
| title_full_unstemmed | Ixekizumab in the treatment of psoriatic arthritis |
| title_short | Ixekizumab in the treatment of psoriatic arthritis |
| title_sort | ixekizumab in the treatment of psoriatic arthritis |
| topic | ixekizumab interleukin 17 inhibitor psoriatic arthritis psoriasis |
| url | https://rsp.mediar-press.net/rsp/article/view/3654 |
| work_keys_str_mv | AT yulkorsakova ixekizumabinthetreatmentofpsoriaticarthritis AT tvkorotaeva ixekizumabinthetreatmentofpsoriaticarthritis |