New Curcumin Analogue (PAC) Inhibits <i>Candida albicans</i> Virulence, Restricts Its Adhesion Potential, and Relieves Oral Epithelial Cell Inflammation and Defense Mechanisms

New Curcumin Analogue (PAC) Inhibits <i>Candida albicans</i> Virulence, Restricts Its Adhesion Potential, and Relieves Oral Epithelial Cell Inflammation and Defense Mechanisms

<b>Objectives:</b> The oral cavity hosts one of the most complex microbial communities in the body. A disruption of the balance favors the growth of pathogenic species, contributing to oral diseases. The rise in microbial resistance has limited the effectiveness of conventional treatment...

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Bibliographic Details
Main Authors: Ghazoua Mezni, Hawraa Issa, Manal Dahdah, Anaïs Poulin, Adam Daïch, Abdulaziz Alamri, Mahmoud Rouabhia, Abdelhabib Semlali
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antibiotics
Subjects:
PAC
<i>C. albicans</i>
virulence
SAPs genes
cytokines
anti-microbial β-defensins
Online Access:https://www.mdpi.com/2079-6382/14/5/495
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