Homicide and Associated Steroid Acute Psychosis: A Case Report

We report the case of an old man treated with methylprednisolone for chronic lymphoid leukemia. After two months of treatment, he declared an acute steroid psychosis and beat his wife to death. Steroids were stopped and the psychotic symptoms subsided, but his condition declined very quickly. The cl...

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Main Authors: G. Airagnes, C. Rouge-Maillart, J.-B. Garre, B. Gohier
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2011/564521
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author G. Airagnes
C. Rouge-Maillart
J.-B. Garre
B. Gohier
author_facet G. Airagnes
C. Rouge-Maillart
J.-B. Garre
B. Gohier
author_sort G. Airagnes
collection DOAJ
description We report the case of an old man treated with methylprednisolone for chronic lymphoid leukemia. After two months of treatment, he declared an acute steroid psychosis and beat his wife to death. Steroids were stopped and the psychotic symptoms subsided, but his condition declined very quickly. The clinical course was complicated by a major depressive disorder with suicidal ideas, due to the steroid stoppage, the leukemia progressed, and by a sudden onset of a fatal pulmonary embolism. This clinical case highlights the importance of early detection of steroid psychosis and proposes, should treatment not be stopped, a strategy of dose reduction combined with a mood stabilizer or antipsychotic treatment. In addition have been revised the risks of the adverse psychiatric effects of steroids.
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institution Kabale University
issn 1687-9627
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language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-0c746925175f47f6b8645a5135ceb4d22025-02-03T01:11:46ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/564521564521Homicide and Associated Steroid Acute Psychosis: A Case ReportG. Airagnes0C. Rouge-Maillart1J.-B. Garre2B. Gohier3Service de Médecine Légale, CHU d'Angers, 49933 Angers Cedex 09, FranceService de Médecine Légale, CHU d'Angers, 49933 Angers Cedex 09, FranceDépartement de Psychiatrie et de Psychologie médicale, CHU d'Angers, 49933 Angers Cedex 09, FranceDépartement de Psychiatrie et de Psychologie médicale, CHU d'Angers, 49933 Angers Cedex 09, FranceWe report the case of an old man treated with methylprednisolone for chronic lymphoid leukemia. After two months of treatment, he declared an acute steroid psychosis and beat his wife to death. Steroids were stopped and the psychotic symptoms subsided, but his condition declined very quickly. The clinical course was complicated by a major depressive disorder with suicidal ideas, due to the steroid stoppage, the leukemia progressed, and by a sudden onset of a fatal pulmonary embolism. This clinical case highlights the importance of early detection of steroid psychosis and proposes, should treatment not be stopped, a strategy of dose reduction combined with a mood stabilizer or antipsychotic treatment. In addition have been revised the risks of the adverse psychiatric effects of steroids.http://dx.doi.org/10.1155/2011/564521
spellingShingle G. Airagnes
C. Rouge-Maillart
J.-B. Garre
B. Gohier
Homicide and Associated Steroid Acute Psychosis: A Case Report
Case Reports in Medicine
title Homicide and Associated Steroid Acute Psychosis: A Case Report
title_full Homicide and Associated Steroid Acute Psychosis: A Case Report
title_fullStr Homicide and Associated Steroid Acute Psychosis: A Case Report
title_full_unstemmed Homicide and Associated Steroid Acute Psychosis: A Case Report
title_short Homicide and Associated Steroid Acute Psychosis: A Case Report
title_sort homicide and associated steroid acute psychosis a case report
url http://dx.doi.org/10.1155/2011/564521
work_keys_str_mv AT gairagnes homicideandassociatedsteroidacutepsychosisacasereport
AT crougemaillart homicideandassociatedsteroidacutepsychosisacasereport
AT jbgarre homicideandassociatedsteroidacutepsychosisacasereport
AT bgohier homicideandassociatedsteroidacutepsychosisacasereport