Self-powered intracellular nanogenerator attenuates inflammatory osteolysis through mitochondrial MRS2/Mg2+-mediated macrophage repolarization and osteoclastogenesis inhibition

Self-powered intracellular nanogenerator attenuates inflammatory osteolysis through mitochondrial MRS2/Mg2+-mediated macrophage repolarization and osteoclastogenesis inhibition

Inflammatory bone resorption is present in common oral and maxillofacial diseases. Macrophages play a crucial role in the inflammatory process of bone. It has been shown that M1 macrophages cause bone homeostasis and bone resorption disorders, and M2 macrophage-related cytokines inhibit osteoclast g...

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Bibliographic Details
Main Authors: Jiyuan Zuo, Qining Guo, Youzhun Fan, Xiaobin Fu, Fengyuan Zhang, Xiaojing Zhu, Chengyun Ning, Yuanyuan Kong, Peng Yu, Jianmao Zheng
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Materials Today Bio
Subjects:
Piezoelectric nanoparticles
Macrophage
Osteoclast
Inflammatory osteolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425006209
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