On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers
A soluble IL-2 receptor (sIL-2R) is a circulating form of a membrane receptor localized on lymphoid and some cancer cells. The biological function of sIL-2R has not been completely understood. Substantially, it seems to reflect T-lymphocyte activation in diseases of different pathology. Moreover, th...
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| Format: | Article |
| Language: | English |
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Wiley
2005-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/MI.2005.121 |
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| _version_ | 1849308851955826688 |
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| author | Anna Maria Witkowska |
| author_facet | Anna Maria Witkowska |
| author_sort | Anna Maria Witkowska |
| collection | DOAJ |
| description | A soluble IL-2 receptor (sIL-2R) is a circulating form of a membrane receptor localized on lymphoid and some cancer cells. The biological function of sIL-2R has not been completely understood. Substantially, it seems to reflect T-lymphocyte activation in
diseases of different pathology. Moreover, the soluble receptor has been considered, at least in part, responsible for unsuccessful immunotherapy with IL-2 in cancers. Several lines of evidence indicate sIL-2R measurements to be useful in determining disease progress and prognosis. This review summarizes current knowledge on the sIL-2R behavior in RA and solid cancers of varied etiology. |
| format | Article |
| id | doaj-art-0c5d864bfc284fb6846368e2cc839ea5 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-0c5d864bfc284fb6846368e2cc839ea52025-08-20T03:54:19ZengWileyMediators of Inflammation0962-93511466-18612005-01-012005312113010.1155/MI.2005.121On the Role of sIL-2R Measurements in Rheumatoid Arthritis and CancersAnna Maria Witkowska0Department of Food Commodities Science and Technology, Medical University of Bialystok, Kilinskiego 1, Bialystok 15-089, PolandA soluble IL-2 receptor (sIL-2R) is a circulating form of a membrane receptor localized on lymphoid and some cancer cells. The biological function of sIL-2R has not been completely understood. Substantially, it seems to reflect T-lymphocyte activation in diseases of different pathology. Moreover, the soluble receptor has been considered, at least in part, responsible for unsuccessful immunotherapy with IL-2 in cancers. Several lines of evidence indicate sIL-2R measurements to be useful in determining disease progress and prognosis. This review summarizes current knowledge on the sIL-2R behavior in RA and solid cancers of varied etiology.http://dx.doi.org/10.1155/MI.2005.121 |
| spellingShingle | Anna Maria Witkowska On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers Mediators of Inflammation |
| title | On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers |
| title_full | On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers |
| title_fullStr | On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers |
| title_full_unstemmed | On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers |
| title_short | On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers |
| title_sort | on the role of sil 2r measurements in rheumatoid arthritis and cancers |
| url | http://dx.doi.org/10.1155/MI.2005.121 |
| work_keys_str_mv | AT annamariawitkowska ontheroleofsil2rmeasurementsinrheumatoidarthritisandcancers |