Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists
Abstract Little is known on how a short‐term reduction of training volume changes muscle proteome and physiological parameters. We investigated the impact of halving training volume during regular training of cyclists on physiological parameters in relation to vastus lateralis protein profiles and f...
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2025-04-01
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| Online Access: | https://doi.org/10.14814/phy2.70302 |
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| author | Pieter deLange Giuseppe Petito Hannah L. Notbohm Antonia Giacco Giovanni Renzone Elena Silvestri Arianna Cuomo Frank Suhr Thorsten Schiffer Jonas Zacher Federica Cioffi Rosalba Senese Andrea Scaloni Moritz Schumann Wilhelm Bloch |
| author_facet | Pieter deLange Giuseppe Petito Hannah L. Notbohm Antonia Giacco Giovanni Renzone Elena Silvestri Arianna Cuomo Frank Suhr Thorsten Schiffer Jonas Zacher Federica Cioffi Rosalba Senese Andrea Scaloni Moritz Schumann Wilhelm Bloch |
| author_sort | Pieter deLange |
| collection | DOAJ |
| description | Abstract Little is known on how a short‐term reduction of training volume changes muscle proteome and physiological parameters. We investigated the impact of halving training volume during regular training of cyclists on physiological parameters in relation to vastus lateralis protein profiles and fiber percentage ratios. Fifteen male cyclists (age: 30.1 ± 9.6 yrs.; VO2max: 59.4 ± 4.4 mL∙kg−1∙min−1; weekly training volume: 8.7 ± 2.3 h) participated in an 11‐week training intervention. During 2 weeks after a shared training programme for 9 weeks, a control group continued training and a taper group reduced training volume by 50%. No end‐point differences were found for peak power output, maximal oxygen uptake, or peak and mean power in a sprint test (p > 0.05), although in the taper group, muscle proteins involved in mitochondrial aerobic respiration increased whereas those involved in translation, protein catabolism, and actin organization decreased, without between‐group differences in type I/type II fiber percentage ratios. Tapering did not decrease power at the first (LT1) and second lactate threshold (LT2) compared to t0, whereas power increased in the control group (LT1: 216 ± 28 W vs. 238 ± 11 W, p = 0.042, LT2: 290 ± 42 W vs. 318 ± 13 W, p = 0.005). Our data indicate that transient 50% training volume reductions may be beneficial for oxidative metabolism in muscle. |
| format | Article |
| id | doaj-art-0c59285de55c4be09a9c4a52abd67dc0 |
| institution | Kabale University |
| issn | 2051-817X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj-art-0c59285de55c4be09a9c4a52abd67dc02025-08-20T03:53:23ZengWileyPhysiological Reports2051-817X2025-04-01138n/an/a10.14814/phy2.70302Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclistsPieter deLange0Giuseppe Petito1Hannah L. Notbohm2Antonia Giacco3Giovanni Renzone4Elena Silvestri5Arianna Cuomo6Frank Suhr7Thorsten Schiffer8Jonas Zacher9Federica Cioffi10Rosalba Senese11Andrea Scaloni12Moritz Schumann13Wilhelm Bloch14Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies University of Campania “Luigi Vanvitelli” Caserta ItalyDepartment of Environmental, Biological, and Pharmaceutical Sciences and Technologies University of Campania “Luigi Vanvitelli” Caserta ItalyDepartment of Molecular and Cellular Sport Medicine German Sports University Cologne GermanyDepartment of Sciences and Technologies University of Sannio Benevento ItalyProteomics, Metabolomics and Mass Spectrometry Laboratory ISPAAM, National Research Council Portici ItalyDepartment of Sciences and Technologies University of Sannio Benevento ItalyDepartment of Environmental, Biological, and Pharmaceutical Sciences and Technologies University of Campania “Luigi Vanvitelli” Caserta ItalyDivision of Molecular Exercise Physiology, Faculty of Life Sciences: Food, Nutrition and Health University of Bayreuth Kulmbach GermanyOutpatient Clinic for Sports Traumatology and Public Health Consultation German Sports University Cologne GermanyDepartment of Preventative and Rehabilitative Sports and Performance Medicine, Institute of Cardiovascular Research and Sports Medicine German Sports University Cologne GermanyDepartment of Sciences and Technologies University of Sannio Benevento ItalyDepartment of Environmental, Biological, and Pharmaceutical Sciences and Technologies University of Campania “Luigi Vanvitelli” Caserta ItalyProteomics, Metabolomics and Mass Spectrometry Laboratory ISPAAM, National Research Council Portici ItalyDepartment of Sports Medicine and Exercise Therapy Chemnitz University of Technology Chemnitz GermanyDepartment of Molecular and Cellular Sport Medicine German Sports University Cologne GermanyAbstract Little is known on how a short‐term reduction of training volume changes muscle proteome and physiological parameters. We investigated the impact of halving training volume during regular training of cyclists on physiological parameters in relation to vastus lateralis protein profiles and fiber percentage ratios. Fifteen male cyclists (age: 30.1 ± 9.6 yrs.; VO2max: 59.4 ± 4.4 mL∙kg−1∙min−1; weekly training volume: 8.7 ± 2.3 h) participated in an 11‐week training intervention. During 2 weeks after a shared training programme for 9 weeks, a control group continued training and a taper group reduced training volume by 50%. No end‐point differences were found for peak power output, maximal oxygen uptake, or peak and mean power in a sprint test (p > 0.05), although in the taper group, muscle proteins involved in mitochondrial aerobic respiration increased whereas those involved in translation, protein catabolism, and actin organization decreased, without between‐group differences in type I/type II fiber percentage ratios. Tapering did not decrease power at the first (LT1) and second lactate threshold (LT2) compared to t0, whereas power increased in the control group (LT1: 216 ± 28 W vs. 238 ± 11 W, p = 0.042, LT2: 290 ± 42 W vs. 318 ± 13 W, p = 0.005). Our data indicate that transient 50% training volume reductions may be beneficial for oxidative metabolism in muscle.https://doi.org/10.14814/phy2.70302aerobic capacityfiber percentage ratioprotein profilethreshold powertraining intensitytraining volume |
| spellingShingle | Pieter deLange Giuseppe Petito Hannah L. Notbohm Antonia Giacco Giovanni Renzone Elena Silvestri Arianna Cuomo Frank Suhr Thorsten Schiffer Jonas Zacher Federica Cioffi Rosalba Senese Andrea Scaloni Moritz Schumann Wilhelm Bloch Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists Physiological Reports aerobic capacity fiber percentage ratio protein profile threshold power training intensity training volume |
| title | Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists |
| title_full | Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists |
| title_fullStr | Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists |
| title_full_unstemmed | Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists |
| title_short | Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists |
| title_sort | unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists |
| topic | aerobic capacity fiber percentage ratio protein profile threshold power training intensity training volume |
| url | https://doi.org/10.14814/phy2.70302 |
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