Cleavage sequence specificity of Nsp15

Nsp15 is an EndoU nuclease that is partially responsible for SARS-CoV-2’s ability to evade the immune system response. Despite its importance, the sequence specificity of Nsp15 remains difficult to fully determine. In this work, we use a systematic approach to measure Nsp15’s sequence specificity by...

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Bibliographic Details
Main Authors: John V. McGuire, Scott Horowitz
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:RNA Biology
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Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2025.2501714
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