Comparative Analysis of Host Cell Entry Efficiency and Neutralization Sensitivity of Emerging SARS-CoV-2 Lineages KP.2, KP.2.3, KP.3, and LB.1

Comparative Analysis of Host Cell Entry Efficiency and Neutralization Sensitivity of Emerging SARS-CoV-2 Lineages KP.2, KP.2.3, KP.3, and LB.1

New SARS-CoV-2 lineages continue to evolve and may exhibit new characteristics regarding host cell entry efficiency and potential for antibody evasion. Here, employing pseudotyped particles, we compared the host cell entry efficiency, ACE2 receptor usage, and sensitivity to antibody-mediated neutral...

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Bibliographic Details
Main Authors: Nianzhen Chen, Katharina Emma Decker, Sebastian R. Schulz, Amy Kempf, Inga Nehlmeier, Anna-Sophie Moldenhauer, Alexandra Dopfer-Jablonka, Georg M. N. Behrens, Metodi V. Stankov, Luis Manthey, Hans-Martin Jäck, Markus Hoffmann, Stefan Pöhlmann, Prerna Arora
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Vaccines
Subjects:
SARS-CoV-2 lineages
ACE2 receptor interactions
antibody evasion
Online Access:https://www.mdpi.com/2076-393X/12/11/1236
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