Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 Years
The majority of children born with very low birth weight (VLBW; < 1500 g) enter mainstream schools. They experience significant neurodevelopmental disabilities during childhood. The specific aims of our study were to evaluate the neonatal outcomes of VLBW infants and whether they would influence...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2008-04-01
|
| Series: | Pediatrics and Neonatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957208600054 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850206013537386496 |
|---|---|
| author | Shu-Chi Mu Cheng-Hui Lin Yi-Ling Chen Chia-Han Chang Kuo-Inn Tsou |
| author_facet | Shu-Chi Mu Cheng-Hui Lin Yi-Ling Chen Chia-Han Chang Kuo-Inn Tsou |
| author_sort | Shu-Chi Mu |
| collection | DOAJ |
| description | The majority of children born with very low birth weight (VLBW; < 1500 g) enter mainstream schools. They experience significant neurodevelopmental disabilities during childhood. The specific aims of our study were to evaluate the neonatal outcomes of VLBW infants and whether they would influence intelligence quotient (IQ), cognitive function and learning disabilities at the age of 6 or 8 years.
Methods: We enrolled VLBW neonates who weighed less than 1500 g and who were delivered at Shin-Kong Wu Ho-Su Memorial Hospital in 1996 and 1999. The psychological assessments were applied with the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) for age 6 and Wechsler Intelligence Scale for Children-Third Edition (WISC-III) for age 8. We recorded their demographic data, ventilation duration by days, length of stay, use of surfactant, respiratory distress syndrome (RDS), and other complications.
Results: According to whether the full scale intelligence quotient (FSIQ) was above or below the average score (FSIQ = 90), we divided VLBW children into two groups (< 90, n = 17; ≥ 90, n = 21). The children with lower gestational age had lower FSIQ (p = 0.013). The higher FSIQ group (≥ 90) showed more prenatal steroid use (5/17, 29.4% vs. 14/21, 66.7%; p = 0.049). There were more boys in the lower FSIQ group (< 90, 13/17, 76.5% vs. ≥90, 7/21, 33.3%; p = 0.011). The average IQ scores were 78.11 ± 9.05 and 102.57 ± 8.89 in the FSIQ < 90 and FSIQ < 90 groups, respectively. The groups were similar in ventilation duration by days, use of surfactant, frequency of sepsis, RDS, bronchopulmonary dysplasia, patent ductus arteriosus, intraventricular hemorrhage and retinopathy of prematurity.
Conclusion: Conclusion: In our study, the children with lower gestational age had lower FSIQ. There was no significant association between small for gestational age and IQ performance. The neonatal outcomes of VLBW infants did have less impact on IQ performance later in life. |
| format | Article |
| id | doaj-art-0c54007243ca47c7b17d7932b63112e4 |
| institution | OA Journals |
| issn | 1875-9572 |
| language | English |
| publishDate | 2008-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-0c54007243ca47c7b17d7932b63112e42025-08-20T02:10:57ZengElsevierPediatrics and Neonatology1875-95722008-04-01492131810.1016/S1875-9572(08)60005-4Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 YearsShu-Chi Mu0Cheng-Hui Lin1Yi-Ling Chen2Chia-Han Chang3Kuo-Inn Tsou4Department of Pediatrics, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, TaiwanCollege of Medicine, Fu Jen Catholic University, Taipei, TaiwanThe majority of children born with very low birth weight (VLBW; < 1500 g) enter mainstream schools. They experience significant neurodevelopmental disabilities during childhood. The specific aims of our study were to evaluate the neonatal outcomes of VLBW infants and whether they would influence intelligence quotient (IQ), cognitive function and learning disabilities at the age of 6 or 8 years. Methods: We enrolled VLBW neonates who weighed less than 1500 g and who were delivered at Shin-Kong Wu Ho-Su Memorial Hospital in 1996 and 1999. The psychological assessments were applied with the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) for age 6 and Wechsler Intelligence Scale for Children-Third Edition (WISC-III) for age 8. We recorded their demographic data, ventilation duration by days, length of stay, use of surfactant, respiratory distress syndrome (RDS), and other complications. Results: According to whether the full scale intelligence quotient (FSIQ) was above or below the average score (FSIQ = 90), we divided VLBW children into two groups (< 90, n = 17; ≥ 90, n = 21). The children with lower gestational age had lower FSIQ (p = 0.013). The higher FSIQ group (≥ 90) showed more prenatal steroid use (5/17, 29.4% vs. 14/21, 66.7%; p = 0.049). There were more boys in the lower FSIQ group (< 90, 13/17, 76.5% vs. ≥90, 7/21, 33.3%; p = 0.011). The average IQ scores were 78.11 ± 9.05 and 102.57 ± 8.89 in the FSIQ < 90 and FSIQ < 90 groups, respectively. The groups were similar in ventilation duration by days, use of surfactant, frequency of sepsis, RDS, bronchopulmonary dysplasia, patent ductus arteriosus, intraventricular hemorrhage and retinopathy of prematurity. Conclusion: Conclusion: In our study, the children with lower gestational age had lower FSIQ. There was no significant association between small for gestational age and IQ performance. The neonatal outcomes of VLBW infants did have less impact on IQ performance later in life.http://www.sciencedirect.com/science/article/pii/S1875957208600054full scale intelligence quotientvery low birth weightWechsler Intelligence Scale for Children-Third EditionWechsler Preschool and Primary Scale of Intelligence |
| spellingShingle | Shu-Chi Mu Cheng-Hui Lin Yi-Ling Chen Chia-Han Chang Kuo-Inn Tsou Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 Years Pediatrics and Neonatology full scale intelligence quotient very low birth weight Wechsler Intelligence Scale for Children-Third Edition Wechsler Preschool and Primary Scale of Intelligence |
| title | Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 Years |
| title_full | Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 Years |
| title_fullStr | Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 Years |
| title_full_unstemmed | Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 Years |
| title_short | Relationship Between Perinatal and Neonatal Indices and Intelligence Quotient in Very Low Birth Weight Infants at the Age of 6 or 8 Years |
| title_sort | relationship between perinatal and neonatal indices and intelligence quotient in very low birth weight infants at the age of 6 or 8 years |
| topic | full scale intelligence quotient very low birth weight Wechsler Intelligence Scale for Children-Third Edition Wechsler Preschool and Primary Scale of Intelligence |
| url | http://www.sciencedirect.com/science/article/pii/S1875957208600054 |
| work_keys_str_mv | AT shuchimu relationshipbetweenperinatalandneonatalindicesandintelligencequotientinverylowbirthweightinfantsattheageof6or8years AT chenghuilin relationshipbetweenperinatalandneonatalindicesandintelligencequotientinverylowbirthweightinfantsattheageof6or8years AT yilingchen relationshipbetweenperinatalandneonatalindicesandintelligencequotientinverylowbirthweightinfantsattheageof6or8years AT chiahanchang relationshipbetweenperinatalandneonatalindicesandintelligencequotientinverylowbirthweightinfantsattheageof6or8years AT kuoinntsou relationshipbetweenperinatalandneonatalindicesandintelligencequotientinverylowbirthweightinfantsattheageof6or8years |