Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis
ATP7A genetic mutations lead to Menkes disease (MD), a hereditary neurodegenerative disorder develops significant metabolic abnormalities including copper deficiency and hypomyelination, and even death before 3 years old. However, the underlying mechanisms remain poorly understood. In this study, a...
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| Main Authors: | You Wu, Jiahuan Li, Wenya Zhai, Wenye Liu, Hao Wu, Hong Liu, Junxia Min, Fudi Wang, Jing-Xia Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996125002438 |
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