Substrate specificity within a family of outer membrane carboxylate channels.

Substrate specificity within a family of outer membrane carboxylate channels.

Many Gram-negative bacteria, including human pathogens such as Pseudomonas aeruginosa, do not have large-channel porins. This results in an outer membrane (OM) that is highly impermeable to small polar molecules, making the bacteria intrinsically resistant towards many antibiotics. In such microorga...

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Bibliographic Details
Main Authors: Elif Eren, Jagamya Vijayaraghavan, Jiaming Liu, Belete R Cheneke, Debra S Touw, Bryan W Lepore, Mridhu Indic, Liviu Movileanu, Bert van den Berg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001242&type=printable
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