Antibiotic residues in dairy products in Africa: A systematic review

The improper use of antibiotics in animal production in Africa may result in antibiotic residues (AR's) in food, and it represents a risk to public health. However, there is scarce information on the rate of AR's in dairy products. This systematic review was performed following the Preferr...

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Main Authors: Emelda Orlando Simbine-Ribisse, Níura Madalena Bila, Agnaldo Joaquim Manhiça, Cristiano João Macuamule, Adriana Pavesi Arisseto Bragotto
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Food Chemistry Advances
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772753X2400217X
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author Emelda Orlando Simbine-Ribisse
Níura Madalena Bila
Agnaldo Joaquim Manhiça
Cristiano João Macuamule
Adriana Pavesi Arisseto Bragotto
author_facet Emelda Orlando Simbine-Ribisse
Níura Madalena Bila
Agnaldo Joaquim Manhiça
Cristiano João Macuamule
Adriana Pavesi Arisseto Bragotto
author_sort Emelda Orlando Simbine-Ribisse
collection DOAJ
description The improper use of antibiotics in animal production in Africa may result in antibiotic residues (AR's) in food, and it represents a risk to public health. However, there is scarce information on the rate of AR's in dairy products. This systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The information was collected from databases Web of Science, Science Direct, PubMed, Google Scholar, PAMJ One Health, ResearchGate, and selected African journals. A total of 359 articles were identified and only 22 studies were included. In total, 6246 dairy samples were analyzed, with raw milk as the main sample (90.7 %). Among the 39 antibiotics recorded, the most detected were penicillin, ampicillin, amoxicillin, oxytetracycline, tetracycline, and chlortetracycline. The highest residue rates (90.38 %) were found for dicloxacillin, cefazolin, cefoperazone, cefaclor, and spiramycin. The most used techniques for antibiotic detection were Delvotest, high-performance liquid chromatography coupled to ultra-violet, and liquid chromatography coupled with mass spectrometry in tandem. AR's are high in raw milk and above the Maximum Residues Level representing a big challenge for Africa. Establishing AR's control plans in Africa could be a good strategy to improve the monitoring of their occurrence in food.
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spelling doaj-art-0c3e34c2d1fb41ffa0ce9c768cae2c102025-08-20T01:59:34ZengElsevierFood Chemistry Advances2772-753X2024-12-01510082210.1016/j.focha.2024.100822Antibiotic residues in dairy products in Africa: A systematic reviewEmelda Orlando Simbine-Ribisse0Níura Madalena Bila1Agnaldo Joaquim Manhiça2Cristiano João Macuamule3Adriana Pavesi Arisseto Bragotto4Department of Food Science and Nutrition, Faculty of Food Engineering, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil; Department of Animal Production and Food Technology, Veterinary Faculty, Universidade Eduardo Mondlane, Maputo, Mozambique; Corresponding author at: Campinas, SP, 13084-600, Brazil.Section of Pharmacology and Toxicology, Department of Public and Animal Health, Veterinary Faculty, Universidade Eduardo Mondlane, Maputo, MozambiqueSection of Food Safety, Department of Public and Animal Health, Veterinary Faculty, Universidade Eduardo Mondlane, Maputo, MozambiqueSection of Pharmacology and Toxicology, Department of Public and Animal Health, Veterinary Faculty, Universidade Eduardo Mondlane, Maputo, MozambiqueDepartment of Food Science and Nutrition, Faculty of Food Engineering, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, BrazilThe improper use of antibiotics in animal production in Africa may result in antibiotic residues (AR's) in food, and it represents a risk to public health. However, there is scarce information on the rate of AR's in dairy products. This systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The information was collected from databases Web of Science, Science Direct, PubMed, Google Scholar, PAMJ One Health, ResearchGate, and selected African journals. A total of 359 articles were identified and only 22 studies were included. In total, 6246 dairy samples were analyzed, with raw milk as the main sample (90.7 %). Among the 39 antibiotics recorded, the most detected were penicillin, ampicillin, amoxicillin, oxytetracycline, tetracycline, and chlortetracycline. The highest residue rates (90.38 %) were found for dicloxacillin, cefazolin, cefoperazone, cefaclor, and spiramycin. The most used techniques for antibiotic detection were Delvotest, high-performance liquid chromatography coupled to ultra-violet, and liquid chromatography coupled with mass spectrometry in tandem. AR's are high in raw milk and above the Maximum Residues Level representing a big challenge for Africa. Establishing AR's control plans in Africa could be a good strategy to improve the monitoring of their occurrence in food.http://www.sciencedirect.com/science/article/pii/S2772753X2400217XVeterinary drugsMilkDetection techniquesFood safetyAfrica
spellingShingle Emelda Orlando Simbine-Ribisse
Níura Madalena Bila
Agnaldo Joaquim Manhiça
Cristiano João Macuamule
Adriana Pavesi Arisseto Bragotto
Antibiotic residues in dairy products in Africa: A systematic review
Food Chemistry Advances
Veterinary drugs
Milk
Detection techniques
Food safety
Africa
title Antibiotic residues in dairy products in Africa: A systematic review
title_full Antibiotic residues in dairy products in Africa: A systematic review
title_fullStr Antibiotic residues in dairy products in Africa: A systematic review
title_full_unstemmed Antibiotic residues in dairy products in Africa: A systematic review
title_short Antibiotic residues in dairy products in Africa: A systematic review
title_sort antibiotic residues in dairy products in africa a systematic review
topic Veterinary drugs
Milk
Detection techniques
Food safety
Africa
url http://www.sciencedirect.com/science/article/pii/S2772753X2400217X
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