Potentiating intratumoral therapy with immune checkpoint inhibitors: shifting the paradigm of multimodality therapeutics
Immune checkpoint inhibitors (ICIs) have revolutionized oncology, yielding remarkable and durable responses in various cancers. However, a significant proportion of patients develop resistance to ICIs. The tumor microenvironment plays a critical role in immunotherapy resistance, characterized by imm...
Saved in:
| Main Authors: | B.E. Nelson, A. Naing, S. Fu, R.A. Sheth, R. Murthy, S. Piha-Paul |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
|
| Series: | Immuno-Oncology and Technology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S259001882400337X |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Intratumoral IL12 mRNA administration activates innate and adaptive pathways in checkpoint inhibitor-resistant tumors resulting in complete responses
by: Jayalakshmi Lakshmipathi, et al.
Published: (2025-06-01) -
Lefitolimod in Combination with Ipilimumab in Patients with Advanced Solid Tumors: A Phase I Trial
by: Mirella Nardo, et al.
Published: (2025-02-01) -
Does Pre-Existing Chronic Obstructive Pulmonary Disease Increase the Risk of Checkpoint Inhibitor Pneumonitis in Advanced/Metastatic Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors?
by: David Spillane, et al.
Published: (2025-04-01) -
A Delayed Presentation of Immune Checkpoint Inhibitor Colitis
by: Alicia Nahhas, et al.
Published: (2025-06-01) -
Resistance to immune checkpoint inhibitors in the treatment of metastatic renal cancer
by: A. A. Izmailov, et al.
Published: (2023-09-01)