Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain

Suzetrigine is the first and only FDA-approved non-opioid oral medication designed to be used for the treatment of moderate-to-severe acute pain. It represents a significant step forward in pain treatment by providing excellent relief without the hazards associated with opiate usage. Its approval tr...

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Main Authors: Konica Chittoria, Ankur Sharma, Nikhil Kothari, Kamlesh Kumari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-07-01
Series:Saudi Journal of Anaesthesia
Subjects:
Online Access:https://journals.lww.com/10.4103/sja.sja_366_25
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author Konica Chittoria
Ankur Sharma
Nikhil Kothari
Kamlesh Kumari
author_facet Konica Chittoria
Ankur Sharma
Nikhil Kothari
Kamlesh Kumari
author_sort Konica Chittoria
collection DOAJ
description Suzetrigine is the first and only FDA-approved non-opioid oral medication designed to be used for the treatment of moderate-to-severe acute pain. It represents a significant step forward in pain treatment by providing excellent relief without the hazards associated with opiate usage. Its approval transforms postoperative pain care, meeting a key public health need while lowering addiction concerns. While the adverse effect profile requires additional investigation, its distinctive mechanism and safety feature represent a game-changing potential in the area of analgesia.
format Article
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institution DOAJ
issn 1658-354X
0975-3125
language English
publishDate 2025-07-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Saudi Journal of Anaesthesia
spelling doaj-art-0c2a88c6889c412dbb2c4444799df05a2025-08-20T02:44:24ZengWolters Kluwer Medknow PublicationsSaudi Journal of Anaesthesia1658-354X0975-31252025-07-0119338438610.4103/sja.sja_366_25Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute painKonica ChittoriaAnkur SharmaNikhil KothariKamlesh KumariSuzetrigine is the first and only FDA-approved non-opioid oral medication designed to be used for the treatment of moderate-to-severe acute pain. It represents a significant step forward in pain treatment by providing excellent relief without the hazards associated with opiate usage. Its approval transforms postoperative pain care, meeting a key public health need while lowering addiction concerns. While the adverse effect profile requires additional investigation, its distinctive mechanism and safety feature represent a game-changing potential in the area of analgesia.https://journals.lww.com/10.4103/sja.sja_366_25analgesiaopioidssuzetrigine
spellingShingle Konica Chittoria
Ankur Sharma
Nikhil Kothari
Kamlesh Kumari
Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain
Saudi Journal of Anaesthesia
analgesia
opioids
suzetrigine
title Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain
title_full Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain
title_fullStr Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain
title_full_unstemmed Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain
title_short Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain
title_sort suzetrigine vx 548 bidding goodbye to opioids the latest oral non opioid analgesic for acute pain
topic analgesia
opioids
suzetrigine
url https://journals.lww.com/10.4103/sja.sja_366_25
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AT ankursharma suzetriginevx548biddinggoodbyetoopioidsthelatestoralnonopioidanalgesicforacutepain
AT nikhilkothari suzetriginevx548biddinggoodbyetoopioidsthelatestoralnonopioidanalgesicforacutepain
AT kamleshkumari suzetriginevx548biddinggoodbyetoopioidsthelatestoralnonopioidanalgesicforacutepain