Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus Control

This work considers the problem of automatically controlling the glucose level in insulin dependent diabetes mellitus (IDDM) patients. The objective is to include several important and practical issues in the design: model uncertainty, time variations, nonlinearities, measurement noise, actuator del...

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Main Authors: R. S. Sánchez Peña, A. S. Ghersin, F. D. Bianchi
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Electrical and Computer Engineering
Online Access:http://dx.doi.org/10.1155/2011/697543
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author R. S. Sánchez Peña
A. S. Ghersin
F. D. Bianchi
author_facet R. S. Sánchez Peña
A. S. Ghersin
F. D. Bianchi
author_sort R. S. Sánchez Peña
collection DOAJ
description This work considers the problem of automatically controlling the glucose level in insulin dependent diabetes mellitus (IDDM) patients. The objective is to include several important and practical issues in the design: model uncertainty, time variations, nonlinearities, measurement noise, actuator delay and saturation, and real time implementation. These are fundamental issues to be solved in a device implementing this control. Two time-varying control procedures have been proposed which take into consideration all of them: linear parameter varying (LPV) and unfalsified control (UC). The controllers are implemented with low-order dynamics that adapt continuously according to the glucose levels measured in real time in one case (LPV) and by controller switching based on the actual performance in the other case (UC). Both controllers have performed adequately under all these practical restrictions, and a discussion on pros and cons of each method is presented at the end.
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issn 2090-0147
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publishDate 2011-01-01
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series Journal of Electrical and Computer Engineering
spelling doaj-art-0c2850c98f484effa91d51e5d7b3659a2025-08-20T03:54:19ZengWileyJournal of Electrical and Computer Engineering2090-01472090-01552011-01-01201110.1155/2011/697543697543Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus ControlR. S. Sánchez Peña0A. S. Ghersin1F. D. Bianchi2CONICET and Center of Systems and Control, Department of Mathematics, Buenos Aires Institute of Technology (ITBA), Avenida E. Madero 399, C1106ACD, Buenos Aires, ArgentinaCONICET and Department of Electrical Engineering, ITBA, Buenos Aires, ArgentinaCatalonia Institute for Energy Research (IREC), Josep Pla, B2, Pl. Baixa, 08019 Barcelona, SpainThis work considers the problem of automatically controlling the glucose level in insulin dependent diabetes mellitus (IDDM) patients. The objective is to include several important and practical issues in the design: model uncertainty, time variations, nonlinearities, measurement noise, actuator delay and saturation, and real time implementation. These are fundamental issues to be solved in a device implementing this control. Two time-varying control procedures have been proposed which take into consideration all of them: linear parameter varying (LPV) and unfalsified control (UC). The controllers are implemented with low-order dynamics that adapt continuously according to the glucose levels measured in real time in one case (LPV) and by controller switching based on the actual performance in the other case (UC). Both controllers have performed adequately under all these practical restrictions, and a discussion on pros and cons of each method is presented at the end.http://dx.doi.org/10.1155/2011/697543
spellingShingle R. S. Sánchez Peña
A. S. Ghersin
F. D. Bianchi
Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus Control
Journal of Electrical and Computer Engineering
title Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus Control
title_full Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus Control
title_fullStr Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus Control
title_full_unstemmed Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus Control
title_short Time-Varying Procedures for Insulin-Dependent Diabetes Mellitus Control
title_sort time varying procedures for insulin dependent diabetes mellitus control
url http://dx.doi.org/10.1155/2011/697543
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