In vitro antibacterial efficacy of a novel chicken-derived Bacillus subtilis GX15 strain and its protective mechanisms in mice challenged by Salmonella enterica serovar typhymurium

In vitro antibacterial efficacy of a novel chicken-derived Bacillus subtilis GX15 strain and its protective mechanisms in mice challenged by Salmonella enterica serovar typhymurium

Abstract Background The escalating issue of bacterial resistance, coupled with stringent restrictions on antibiotic use in many countries, has prompted the search for alternative strategies to combat bacterial infections. Probiotics, such as Bacillus subtilis (B. subtilis), have been widely recogniz...

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Main Authors: Huili Bai, Yuying Liao, Jingshan Lu, Zhe Pei, Yangyan Yin, Chunxia Ma, Zhongwei Chen, Changting Li, Jun Li, Yu Gong, Ling Teng, Leping Wang, Zijuan Su, Hailan Chen, Hao Peng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Microbiology
Subjects:
Probiotic
Bacillus subtilis
Salmonella Typhimurium
Protection
Immunity
Online Access:https://doi.org/10.1186/s12866-025-04107-z
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