Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in context
Summary: Background: People with lower socioeconomic positions have a higher risk of cardiac and infectious diseases than those with higher socioeconomic positions. However, how the increasing incidence of infective endocarditis among different socioeconomic groups has played out remains unclear. W...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | The Lancet Regional Health. Europe |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666776225000596 |
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| author | Søren K. Martiny Morten Schmidt Jonas A. Povlsen Kirstine K. Søgaard Hans E. Bøtker Henrik T. Sørensen |
| author_facet | Søren K. Martiny Morten Schmidt Jonas A. Povlsen Kirstine K. Søgaard Hans E. Bøtker Henrik T. Sørensen |
| author_sort | Søren K. Martiny |
| collection | DOAJ |
| description | Summary: Background: People with lower socioeconomic positions have a higher risk of cardiac and infectious diseases than those with higher socioeconomic positions. However, how the increasing incidence of infective endocarditis among different socioeconomic groups has played out remains unclear. We therefore aimed to investigate nationwide temporal trends in infective endocarditis incidence rate by socioeconomic position in Denmark. Methods: Using nationwide Danish registries, we investigated infective endocarditis incidence rate (2000–2022). As socioeconomic position indicator, we used affluence level (accounting for household-level income and wealth), dividing the population into low, medium, and high affluence. Average annual percentage changes were computed to evaluate temporal trends. Slope index and relative index of inequality were calculated to obtain inequality gradients. Findings: Per 100,000 person-years, the incidence rate increased from 8.7 in 2000 to 21.2 in 2022 among low; from 7.4 to 14.3 among medium; and from 6.2 to 13.1 among high affluence people. The average annual percentage change was 4.3% among low, 3.5% among medium, and 3.7% among high affluence people. The slope index of inequality increased from 3.8 additional cases per 100,000 person years (95% CI: 0.4–7.3) in 2000 to 12.3 (95% CI: 7.4–17.1) in 2022. The relative index of inequality increased from 1.68 (95% CI: 0.90–2.44) to 2.13 (95% CI: 1.49–2.78). Interpretation: The infective endocarditis incidence rates increased in all affluence levels, with highest rates consistently found in the lowest affluence group, indicating that people with lower socioeconomic positions faced a disproportionately higher risk of infective endocarditis. These findings highlight the need to consider socioeconomic factors when addressing modifiable determinants that may curb the rise in infective endocarditis incidence. Funding: Independent Research Fund Denmark (grant no. 3101-00102B) and Center for Population Medicine, Department of Clinical Epidemiology, Aarhus University. |
| format | Article |
| id | doaj-art-0c09019905394ab293da0a8b9c0cd0a3 |
| institution | Kabale University |
| issn | 2666-7762 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | The Lancet Regional Health. Europe |
| spelling | doaj-art-0c09019905394ab293da0a8b9c0cd0a32025-08-20T03:44:11ZengElsevierThe Lancet Regional Health. Europe2666-77622025-05-015210126710.1016/j.lanepe.2025.101267Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in contextSøren K. Martiny0Morten Schmidt1Jonas A. Povlsen2Kirstine K. Søgaard3Hans E. Bøtker4Henrik T. Sørensen5Department of Clinical Epidemiology, Center for Population Medicine, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Corresponding author. Olof Palmes Allé 43–45, 8200, Aarhus N, Denmark.Department of Clinical Epidemiology, Center for Population Medicine, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Department of Cardiology, Gødstrup Regional Hospital, Herning, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Center for Population Medicine, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Department of Microbiology, Aalborg University Hospital, Aalborg, DenmarkDepartment of Clinical Epidemiology, Center for Population Medicine, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Department of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Center for Population Medicine, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, DenmarkSummary: Background: People with lower socioeconomic positions have a higher risk of cardiac and infectious diseases than those with higher socioeconomic positions. However, how the increasing incidence of infective endocarditis among different socioeconomic groups has played out remains unclear. We therefore aimed to investigate nationwide temporal trends in infective endocarditis incidence rate by socioeconomic position in Denmark. Methods: Using nationwide Danish registries, we investigated infective endocarditis incidence rate (2000–2022). As socioeconomic position indicator, we used affluence level (accounting for household-level income and wealth), dividing the population into low, medium, and high affluence. Average annual percentage changes were computed to evaluate temporal trends. Slope index and relative index of inequality were calculated to obtain inequality gradients. Findings: Per 100,000 person-years, the incidence rate increased from 8.7 in 2000 to 21.2 in 2022 among low; from 7.4 to 14.3 among medium; and from 6.2 to 13.1 among high affluence people. The average annual percentage change was 4.3% among low, 3.5% among medium, and 3.7% among high affluence people. The slope index of inequality increased from 3.8 additional cases per 100,000 person years (95% CI: 0.4–7.3) in 2000 to 12.3 (95% CI: 7.4–17.1) in 2022. The relative index of inequality increased from 1.68 (95% CI: 0.90–2.44) to 2.13 (95% CI: 1.49–2.78). Interpretation: The infective endocarditis incidence rates increased in all affluence levels, with highest rates consistently found in the lowest affluence group, indicating that people with lower socioeconomic positions faced a disproportionately higher risk of infective endocarditis. These findings highlight the need to consider socioeconomic factors when addressing modifiable determinants that may curb the rise in infective endocarditis incidence. Funding: Independent Research Fund Denmark (grant no. 3101-00102B) and Center for Population Medicine, Department of Clinical Epidemiology, Aarhus University.http://www.sciencedirect.com/science/article/pii/S2666776225000596Infective endocarditisIncidenceTemporal trendSocioeconomic position |
| spellingShingle | Søren K. Martiny Morten Schmidt Jonas A. Povlsen Kirstine K. Søgaard Hans E. Bøtker Henrik T. Sørensen Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in context The Lancet Regional Health. Europe Infective endocarditis Incidence Temporal trend Socioeconomic position |
| title | Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in context |
| title_full | Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in context |
| title_fullStr | Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in context |
| title_full_unstemmed | Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in context |
| title_short | Incidence rate of infective endocarditis by socioeconomic position: a Danish nationwide cohort study (2000–2022)Research in context |
| title_sort | incidence rate of infective endocarditis by socioeconomic position a danish nationwide cohort study 2000 2022 research in context |
| topic | Infective endocarditis Incidence Temporal trend Socioeconomic position |
| url | http://www.sciencedirect.com/science/article/pii/S2666776225000596 |
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