CDK1 mediates the metabolic regulation of DNA double-strand break repair in metaphase II oocytes
Abstract Background During oocyte maturation, DNA double-strand breaks (DSBs) can decrease oocyte quality or cause mutations. How DSBs are repaired in dividing oocytes and which factors influence DSB repair are not well understood. Results By analyzing DSB repair pathways in oocytes at different sta...
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Main Authors: | Tian-Jin Xia, Feng-Yun Xie, Juan Chen, Xiao-Guohui Zhang, Sen Li, Qing-Yuan Sun, Qin Zhang, Shen Yin, Xiang-Hong Ou, Jun-Yu Ma |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-025-02142-w |
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