Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor 𝛾 with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development

Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor 𝛾 with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development

Exposure to the estrogen receptor alpha (ER𝛼) ligand diethylstilbesterol (DES) between neonatal days 2 to 12 induces penile adipogenesis and adult infertility in rats. The objective of this study was to investigate the in vivo interaction between DES-activated ER𝛼 and the proadipogenic transcription...

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Bibliographic Details
Main Authors: Mahmoud M. Mansour, Hari O. Goyal, Tim D. Braden, John C. Dennis, Dean D. Schwartz, Robert L. Judd, Frank F. Bartol, Elaine S. Coleman, Edward E. Morrison
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2008/651419
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