Synthesis of Spirooxindole-<em>O</em>-Naphthoquinone-Tetrazolo[1,5-<em>a</em>]Pyrimidine Hybrids as Potential Anticancer Agents
A series of novel spirooxindole-<i>O</i>-naphthoquinone-tetrazolo[1,5-<i>a</i>]pyrimidine hybrids were designed, synthesized and evaluated as potent antitumor agents. These hybrids exhibited relatively high cytotoxic activity against cancer cell line HepG2 (IC<sub>50<...
Saved in:
Main Authors: | Liqiang Wu, Yunxia Liu, Yazhen Li |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-09-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/23/9/2330 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Correction: Wu et al. Synthesis of Spirooxindole-<i>O</i>-Naphthoquinone-Tetrazolo[1,5-<i>a</i>]Pyrimidine Hybrids as Potential Anticancer Agents. <i>Molecules</i> 2018, <i>23</i>, 2330
by: Liqiang Wu, et al.
Published: (2024-11-01) -
Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents
by: Yujuan Li, et al.
Published: (2024-12-01) -
Synthesis and Diversification of Chiral Spirooxindoles via Organocatalytic Cascade Reactions
by: Jessica Navarro Vega, et al.
Published: (2023-11-01) -
Nanoformulation of Spirooxindole and Methods for Treating Hepatocellular Carcinoma
by: Assem Barakat, et al.
Published: (2025-01-01) -
Utilizing MEDT analysis of [3 + 2] cycloaddition reaction: x-ray crystallography of spirooxindole linked with thiophene/furan heterocycles and triazole framework
by: Abdulmajeed Abdullah Alayyaf, et al.
Published: (2024-11-01)