Allergic response to nasal administration of dexpanthenol in a child. A case report and a review of the literature
A 2-year-old boy with suspected lactose intolerance developed an extensive, itchy rash after using a nasal spray containing dexpanthenol. He was initially treated for a viral upper airway infection with ibuprofen, xylometazoline, and cetirizine. A switch to a drug containing dexpanthenol led to the...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2024-02-01
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| Series: | Alergologia Polska |
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| Online Access: | https://www.termedia.pl/Allergic-response-to-nasal-administration-of-dexpanthenol-r-nin-a-child-A-case-report-and-a-review-of-the-literature,123,52423,1,1.html |
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| author | Mikołaj Turski Małgorzata Łukasiewicz Piotr Sajdak Seweryn Ziajor Artur Bednarski Justyna Tomasik Marcel Stodolak |
| author_facet | Mikołaj Turski Małgorzata Łukasiewicz Piotr Sajdak Seweryn Ziajor Artur Bednarski Justyna Tomasik Marcel Stodolak |
| author_sort | Mikołaj Turski |
| collection | DOAJ |
| description | A 2-year-old boy with suspected lactose intolerance developed an extensive, itchy rash after using a nasal spray containing dexpanthenol. He was initially treated for a viral upper airway infection with ibuprofen, xylometazoline, and cetirizine. A switch to a drug containing dexpanthenol led to the appearance of the rash and subsequent sleep deprivation. No other possible cause of allergy was found. The withdrawal of all drugs but cetirizine led to full recovery. Dexpanthenol, an alcohol analog of vitamin B5, is present in many drugs for its positive impact on tissue repair. Although generally considered safe, it may rarely cause an allergic reaction, hence we underscore the importance of considering dexpanthenol oversensitivity in patients with unexplained widespread rashes, particularly in pediatric cases. |
| format | Article |
| id | doaj-art-0bdf818507e74f789680c59968721096 |
| institution | Kabale University |
| issn | 2353-3854 2391-6052 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Alergologia Polska |
| spelling | doaj-art-0bdf818507e74f789680c599687210962025-01-27T10:33:52ZengTermedia Publishing HouseAlergologia Polska2353-38542391-60522024-02-01111767910.5114/pja.2024.13550752423Allergic response to nasal administration of dexpanthenol in a child. A case report and a review of the literatureMikołaj TurskiMałgorzata ŁukasiewiczPiotr SajdakSeweryn ZiajorArtur BednarskiJustyna TomasikMarcel StodolakA 2-year-old boy with suspected lactose intolerance developed an extensive, itchy rash after using a nasal spray containing dexpanthenol. He was initially treated for a viral upper airway infection with ibuprofen, xylometazoline, and cetirizine. A switch to a drug containing dexpanthenol led to the appearance of the rash and subsequent sleep deprivation. No other possible cause of allergy was found. The withdrawal of all drugs but cetirizine led to full recovery. Dexpanthenol, an alcohol analog of vitamin B5, is present in many drugs for its positive impact on tissue repair. Although generally considered safe, it may rarely cause an allergic reaction, hence we underscore the importance of considering dexpanthenol oversensitivity in patients with unexplained widespread rashes, particularly in pediatric cases.https://www.termedia.pl/Allergic-response-to-nasal-administration-of-dexpanthenol-r-nin-a-child-A-case-report-and-a-review-of-the-literature,123,52423,1,1.htmlrash dexpanthenol allergy allergic reaction dexpanthenol oversensitivity widespread rash |
| spellingShingle | Mikołaj Turski Małgorzata Łukasiewicz Piotr Sajdak Seweryn Ziajor Artur Bednarski Justyna Tomasik Marcel Stodolak Allergic response to nasal administration of dexpanthenol in a child. A case report and a review of the literature Alergologia Polska rash dexpanthenol allergy allergic reaction dexpanthenol oversensitivity widespread rash |
| title | Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature |
| title_full | Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature |
| title_fullStr | Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature |
| title_full_unstemmed | Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature |
| title_short | Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature |
| title_sort | allergic response to nasal administration of dexpanthenol in a child a case report and a review of the literature |
| topic | rash dexpanthenol allergy allergic reaction dexpanthenol oversensitivity widespread rash |
| url | https://www.termedia.pl/Allergic-response-to-nasal-administration-of-dexpanthenol-r-nin-a-child-A-case-report-and-a-review-of-the-literature,123,52423,1,1.html |
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