The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)

Aim. To present the materials of an Expert Council, which was held on September 23, 2019 in Istanbul (Turkey) under the auspices of a World Gastroenterology Organisation congress and the support of the Abbott company.General provisions. During the work of the Expert Council, the role of motility dis...

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Main Authors: I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, S. R. Abdulhakov, N. A. Agafonova, V. A. Akhmedov, T. A. Ilchishina, M. G. Ipatova, O. V. Krapivnaya, Yu. A. Kucheryavyi, M. F. Osipenko, O. A. Storonova, G. N. Tarasova, G. Ya. Khismatullina, S. V. Cheryomushkin
Format: Article
Language:Russian
Published: Gastro LLC 2020-01-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/447
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author I. V. Maev
A. S. Trukhmanov
A. A. Sheptulin
V. I. Simanenkov
S. R. Abdulhakov
N. A. Agafonova
V. A. Akhmedov
T. A. Ilchishina
M. G. Ipatova
O. V. Krapivnaya
Yu. A. Kucheryavyi
M. F. Osipenko
O. A. Storonova
G. N. Tarasova
G. Ya. Khismatullina
S. V. Cheryomushkin
author_facet I. V. Maev
A. S. Trukhmanov
A. A. Sheptulin
V. I. Simanenkov
S. R. Abdulhakov
N. A. Agafonova
V. A. Akhmedov
T. A. Ilchishina
M. G. Ipatova
O. V. Krapivnaya
Yu. A. Kucheryavyi
M. F. Osipenko
O. A. Storonova
G. N. Tarasova
G. Ya. Khismatullina
S. V. Cheryomushkin
author_sort I. V. Maev
collection DOAJ
description Aim. To present the materials of an Expert Council, which was held on September 23, 2019 in Istanbul (Turkey) under the auspices of a World Gastroenterology Organisation congress and the support of the Abbott company.General provisions. During the work of the Expert Council, the role of motility disorders of the stomach and duodenum, intestines, gall bladder and the sphincter of Oddi in the development of functional diseases of the digestive system, such as functional dyspepsia (FD), irritable bowel syndrome (IBS), biliary dyskinesia (BD) was discussed, and the effectiveness of antispasmodics and prokinetics in their treatment was shown. At the same time, the advantages of the mebeverin antispasmodic drug, as well as the high efficiency and safety of the itopride hydrochloride prokinetic drug were noted. It is emphasized that, at the stage of a diagnostic search in the absence of “alarm symptoms” in patients with suspected FD, IBS, and BD, these drugs can be prescribed empirically.Conclusions. When selecting pharmacotherapy for patients with motor impairment, it is extremely important to consider the nature of these disorders. The use of modern medical preparations, which are characterized by a high level of safety and the targeted action towards a specific motility disorder, allows optimal therapy results to be achieved with minimal risks for the patient.
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spelling doaj-art-0bdf563df53448ee8ef5d381517ee3862025-02-10T16:14:36ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732020-01-0129671410.22416/1382-4376-2019-29-6-7-14332The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)I. V. Maev0A. S. Trukhmanov1A. A. Sheptulin2V. I. Simanenkov3S. R. Abdulhakov4N. A. Agafonova5V. A. Akhmedov6T. A. Ilchishina7M. G. Ipatova8O. V. Krapivnaya9Yu. A. Kucheryavyi10M. F. Osipenko11O. A. Storonova12G. N. Tarasova13G. Ya. Khismatullina14S. V. Cheryomushkin15A.I. Yevdokimov Moscow State University of Medicine and DentistryI.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)North-Western State Medical University named after I.I. MechnikovKazan State Medical UniversityPirogov Russian National Research Medical UniversityOmsk State Medical UniversityMedical Holding “SM-clinic” (“Med Kom”)Pirogov Russian National Research Medical UniversityRoad Clinical Hospital of JSC Russian Railways, Khabarovsk-1 stationA.I. Yevdokimov Moscow State University of Medicine and DentistryNovosibirsk State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)Rostov State Medical UnivesrityBashkir State Medical UniversityA.I. Yevdokimov Moscow State University of Medicine and DentistryAim. To present the materials of an Expert Council, which was held on September 23, 2019 in Istanbul (Turkey) under the auspices of a World Gastroenterology Organisation congress and the support of the Abbott company.General provisions. During the work of the Expert Council, the role of motility disorders of the stomach and duodenum, intestines, gall bladder and the sphincter of Oddi in the development of functional diseases of the digestive system, such as functional dyspepsia (FD), irritable bowel syndrome (IBS), biliary dyskinesia (BD) was discussed, and the effectiveness of antispasmodics and prokinetics in their treatment was shown. At the same time, the advantages of the mebeverin antispasmodic drug, as well as the high efficiency and safety of the itopride hydrochloride prokinetic drug were noted. It is emphasized that, at the stage of a diagnostic search in the absence of “alarm symptoms” in patients with suspected FD, IBS, and BD, these drugs can be prescribed empirically.Conclusions. When selecting pharmacotherapy for patients with motor impairment, it is extremely important to consider the nature of these disorders. The use of modern medical preparations, which are characterized by a high level of safety and the targeted action towards a specific motility disorder, allows optimal therapy results to be achieved with minimal risks for the patient.https://www.gastro-j.ru/jour/article/view/447functional dyspepsiairritable bowel syndromebiliary dyskinesiaantispasmodicsprokineticsmebeverinitopride
spellingShingle I. V. Maev
A. S. Trukhmanov
A. A. Sheptulin
V. I. Simanenkov
S. R. Abdulhakov
N. A. Agafonova
V. A. Akhmedov
T. A. Ilchishina
M. G. Ipatova
O. V. Krapivnaya
Yu. A. Kucheryavyi
M. F. Osipenko
O. A. Storonova
G. N. Tarasova
G. Ya. Khismatullina
S. V. Cheryomushkin
The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
functional dyspepsia
irritable bowel syndrome
biliary dyskinesia
antispasmodics
prokinetics
mebeverin
itopride
title The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)
title_full The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)
title_fullStr The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)
title_full_unstemmed The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)
title_short The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review)
title_sort role of motility impairment in the pathogenesis of functional disorders of the gastrointestinal tract and modern possibilities for their treatment resolution of an expert council and literature review
topic functional dyspepsia
irritable bowel syndrome
biliary dyskinesia
antispasmodics
prokinetics
mebeverin
itopride
url https://www.gastro-j.ru/jour/article/view/447
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