Structural characterization of the full-length Hantaan virus polymerase.

Structural characterization of the full-length Hantaan virus polymerase.

Hantaviridae are a family of segmented negative-sense RNA viruses that contain important human and animal pathogens. Hantaviridae contain a viral RNA-dependent RNA polymerase that replicates and transcribes the viral genome. Here we establish the expression and purification of the polymerase from th...

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Bibliographic Details
Main Authors: Jeremy R Keown, Loïc Carrique, Benjamin E Nilsson-Payant, Ervin Fodor, Jonathan M Grimes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012781
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