Diphtheria Carriage

The diphtheria carriage is a asympthomatic colonization of oro- and nasopharynx by toxigenic and nontoxigenic Corynebacterium diphtheriae. The carriage of toxigenic strains prevents a complete eradication of diphtheria infection in spite of mass toxoid immunization. The contamination by toxigenic di...

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Main Authors: N. N. Kostyukova, V. A. Bechalo
Format: Article
Language:Russian
Published: Numikom LLC 2018-10-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/578
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author N. N. Kostyukova
V. A. Bechalo
author_facet N. N. Kostyukova
V. A. Bechalo
author_sort N. N. Kostyukova
collection DOAJ
description The diphtheria carriage is a asympthomatic colonization of oro- and nasopharynx by toxigenic and nontoxigenic Corynebacterium diphtheriae. The carriage of toxigenic strains prevents a complete eradication of diphtheria infection in spite of mass toxoid immunization. The contamination by toxigenic diphtheria bacteria leads to the carriage if the person has a protective level of diphtheria antitoxin. Contamination with the toxigenic and nontoxigenic leads to the carriage if the person has no protection to the bacterial colonization factors. Some of them are surface protein structures and may serve as components of the future vaccines against diphtheria bacteria colonization.
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institution Kabale University
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publishDate 2018-10-01
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series Эпидемиология и вакцинопрофилактика
spelling doaj-art-0bd7767fe0064a9ab99cc0d7b43be7002025-08-20T03:43:47ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942018-10-01175607010.31631/2073-3046-2018-17-5-60-70469Diphtheria CarriageN. N. Kostyukova0V. A. Bechalo1The Gamaleya National Research Center for Epidemioloy and Microbiology, Ministry of Healthcare of Russian FederationThe Gamaleya National Research Center for Epidemioloy and Microbiology, Ministry of Healthcare of Russian FederationThe diphtheria carriage is a asympthomatic colonization of oro- and nasopharynx by toxigenic and nontoxigenic Corynebacterium diphtheriae. The carriage of toxigenic strains prevents a complete eradication of diphtheria infection in spite of mass toxoid immunization. The contamination by toxigenic diphtheria bacteria leads to the carriage if the person has a protective level of diphtheria antitoxin. Contamination with the toxigenic and nontoxigenic leads to the carriage if the person has no protection to the bacterial colonization factors. Some of them are surface protein structures and may serve as components of the future vaccines against diphtheria bacteria colonization.https://www.epidemvac.ru/jour/article/view/578diphtheria carriagecolonization with corynebacterium diphtheriaecolonization factors of corynebacterium diphtheriaeimmune protection from colonizationantitoxic immunity at diphtheria carriers
spellingShingle N. N. Kostyukova
V. A. Bechalo
Diphtheria Carriage
Эпидемиология и вакцинопрофилактика
diphtheria carriage
colonization with corynebacterium diphtheriae
colonization factors of corynebacterium diphtheriae
immune protection from colonization
antitoxic immunity at diphtheria carriers
title Diphtheria Carriage
title_full Diphtheria Carriage
title_fullStr Diphtheria Carriage
title_full_unstemmed Diphtheria Carriage
title_short Diphtheria Carriage
title_sort diphtheria carriage
topic diphtheria carriage
colonization with corynebacterium diphtheriae
colonization factors of corynebacterium diphtheriae
immune protection from colonization
antitoxic immunity at diphtheria carriers
url https://www.epidemvac.ru/jour/article/view/578
work_keys_str_mv AT nnkostyukova diphtheriacarriage
AT vabechalo diphtheriacarriage