Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)

Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (produced with Talaromyces versatilis DSM 26702 and T. versatilis IMI 378536) (ROVABIO®...

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Main Authors: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Baltasar Mayo, Andrey Yurkov, Montserrat Anguita, Nicole Bozzi Cionci, Rosella Brozzi, Matteo Lorenzo Innocenti, Elisa Pettenati, Jordi Tarrés‐Call, Jaume Galobart
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:EFSA Journal
Subjects:
Online Access:https://doi.org/10.2903/j.efsa.2025.9547
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author EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López‐Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto‐Maradona
Ilen Röhe
Katerina Theodoridou
Baltasar Mayo
Andrey Yurkov
Montserrat Anguita
Nicole Bozzi Cionci
Rosella Brozzi
Matteo Lorenzo Innocenti
Elisa Pettenati
Jordi Tarrés‐Call
Jaume Galobart
author_facet EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López‐Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto‐Maradona
Ilen Röhe
Katerina Theodoridou
Baltasar Mayo
Andrey Yurkov
Montserrat Anguita
Nicole Bozzi Cionci
Rosella Brozzi
Matteo Lorenzo Innocenti
Elisa Pettenati
Jordi Tarrés‐Call
Jaume Galobart
author_sort EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
collection DOAJ
description Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (produced with Talaromyces versatilis DSM 26702 and T. versatilis IMI 378536) (ROVABIO® ADVANCE) as a zootechnical additive (functional group of digestibility enhancers) in feed for all poultry species. The additive is currently authorised for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying. This scientific opinion concerns the request for the renewal of the authorisation of the additive for these species and the extension of use to all poultry species. The applicant provided evidence that the additive complies with the conditions of the authorisation. The FEEDAP Panel concluded that the additive remains safe for the target species, consumers and the environment, and that the extension of use to the new species would not affect these conclusions. Regarding user safety, the FEEDAP Panel reiterates its previous conclusion that the additive is not irritant to the skin or eyes and is to be considered a potential skin and respiratory sensitiser. There is no need for assessing the efficacy of the additive for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying in the context of the renewal of the authorisation. The FEEDAP Panel considers that the additive has the potential to be efficacious in all poultry species at a minimum inclusion level of 1100 VU endo‐1,4‐beta‐xylanase and 760 VU endo‐1,3(4)‐beta‐glucanase/kg complete feed.
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spelling doaj-art-0bd257d273f34c28a1ed7b709f63cd9c2025-08-20T03:58:36ZengWileyEFSA Journal1831-47322025-07-01237n/an/a10.2903/j.efsa.2025.9547Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Roberto Edoardo VillaGiovanna AzimontiEleftherios BonosHenrik ChristensenMojca DurjavaBirgit DusemundRonette GehringBoet GlandorfMaryline KoubaMarta López‐AlonsoFrancesca MarconCarlo NebbiaAlena PechováMiguel Prieto‐MaradonaIlen RöheKaterina TheodoridouBaltasar MayoAndrey YurkovMontserrat AnguitaNicole Bozzi CionciRosella BrozziMatteo Lorenzo InnocentiElisa PettenatiJordi Tarrés‐CallJaume GalobartAbstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (produced with Talaromyces versatilis DSM 26702 and T. versatilis IMI 378536) (ROVABIO® ADVANCE) as a zootechnical additive (functional group of digestibility enhancers) in feed for all poultry species. The additive is currently authorised for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying. This scientific opinion concerns the request for the renewal of the authorisation of the additive for these species and the extension of use to all poultry species. The applicant provided evidence that the additive complies with the conditions of the authorisation. The FEEDAP Panel concluded that the additive remains safe for the target species, consumers and the environment, and that the extension of use to the new species would not affect these conclusions. Regarding user safety, the FEEDAP Panel reiterates its previous conclusion that the additive is not irritant to the skin or eyes and is to be considered a potential skin and respiratory sensitiser. There is no need for assessing the efficacy of the additive for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying in the context of the renewal of the authorisation. The FEEDAP Panel considers that the additive has the potential to be efficacious in all poultry species at a minimum inclusion level of 1100 VU endo‐1,4‐beta‐xylanase and 760 VU endo‐1,3(4)‐beta‐glucanase/kg complete feed.https://doi.org/10.2903/j.efsa.2025.9547digestibility enhancersefficacypoultryROVABIO® ADVANCEsafetyzootechnical additives
spellingShingle EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López‐Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto‐Maradona
Ilen Röhe
Katerina Theodoridou
Baltasar Mayo
Andrey Yurkov
Montserrat Anguita
Nicole Bozzi Cionci
Rosella Brozzi
Matteo Lorenzo Innocenti
Elisa Pettenati
Jordi Tarrés‐Call
Jaume Galobart
Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)
EFSA Journal
digestibility enhancers
efficacy
poultry
ROVABIO® ADVANCE
safety
zootechnical additives
title Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)
title_full Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)
title_fullStr Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)
title_full_unstemmed Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)
title_short Assessment of the feed additive consisting of endo‐1,3(4)‐beta‐glucanase and endo‐1,4‐beta‐xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS)
title_sort assessment of the feed additive consisting of endo 1 3 4 beta glucanase and endo 1 4 beta xylanase rovabio r advance for chickens for fattening and reared for laying laying hens turkeys for fattening and reared for breeding and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species adisseo france sas
topic digestibility enhancers
efficacy
poultry
ROVABIO® ADVANCE
safety
zootechnical additives
url https://doi.org/10.2903/j.efsa.2025.9547
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AT robertoedoardovilla assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT giovannaazimonti assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT eleftheriosbonos assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
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AT birgitdusemund assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
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AT boetglandorf assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
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AT francescamarcon assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT carlonebbia assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT alenapechova assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT miguelprietomaradona assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT ilenrohe assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT katerinatheodoridou assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT baltasarmayo assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT andreyyurkov assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT montserratanguita assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT nicolebozzicionci assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT rosellabrozzi assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT matteolorenzoinnocenti assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT elisapettenati assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT jorditarrescall assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa
AT jaumegalobart assessmentofthefeedadditiveconsistingofendo134betaglucanaseandendo14betaxylanaserovabioadvanceforchickensforfatteningandrearedforlayinglayinghensturkeysforfatteningandrearedforbreedingandminorpoultryspeciesforfatteningandrearedforlayingfortherenewalofitsa