Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.

<h4>Objective</h4>To examine participants' motivations and their experiences throughout a decentralized, longitudinal COVID-19 study in the U.S.<h4>Methods</h4>We recruited 355 participants from the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INS...

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Main Authors: Kris Pui Kwan Ma, Tracy Stober, Michael Gottlieb, Rachel E Geyer, Kristin Rising, Sharon Saydah, Michelle Santangelo, Kristyn Gatling, Dylan Grau, Ralph C Wang, Juan Carlos Montoy, Ahamed Idris, Samuel MacDonald, Mandy J Hill, Ryan Huebinger, Maria G Prado, Nicole L Gentile, Erica Spatz, Caitlin Maliki, Jocelyn Dorney, Joann G Elmore, Michelle L'Hommedieu, Robert A Weinstein, Arjun K Venkatesh, Kari A Stephens, INSPIRE Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325948
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author Kris Pui Kwan Ma
Tracy Stober
Michael Gottlieb
Rachel E Geyer
Kristin Rising
Sharon Saydah
Michelle Santangelo
Kristyn Gatling
Dylan Grau
Ralph C Wang
Juan Carlos Montoy
Ahamed Idris
Samuel MacDonald
Mandy J Hill
Ryan Huebinger
Maria G Prado
Nicole L Gentile
Erica Spatz
Caitlin Maliki
Jocelyn Dorney
Joann G Elmore
Michelle L'Hommedieu
Robert A Weinstein
Arjun K Venkatesh
Kari A Stephens
INSPIRE Group
author_facet Kris Pui Kwan Ma
Tracy Stober
Michael Gottlieb
Rachel E Geyer
Kristin Rising
Sharon Saydah
Michelle Santangelo
Kristyn Gatling
Dylan Grau
Ralph C Wang
Juan Carlos Montoy
Ahamed Idris
Samuel MacDonald
Mandy J Hill
Ryan Huebinger
Maria G Prado
Nicole L Gentile
Erica Spatz
Caitlin Maliki
Jocelyn Dorney
Joann G Elmore
Michelle L'Hommedieu
Robert A Weinstein
Arjun K Venkatesh
Kari A Stephens
INSPIRE Group
author_sort Kris Pui Kwan Ma
collection DOAJ
description <h4>Objective</h4>To examine participants' motivations and their experiences throughout a decentralized, longitudinal COVID-19 study in the U.S.<h4>Methods</h4>We recruited 355 participants from the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE) between November 2022 - March 2023 to answer five qualitative survey questions anonymously. We used an inductive content analysis approach to analyze the data.<h4>Results</h4>We identified five key themes from the analysis, which reflected participants' a) motivations to join the study, b) study benefits, c) perceptions of survey questions, d) experiences with the research process, and e) preferences for disseminating research findings. Participants were motivated to learn with researchers about COVID-19. They expressed divided opinions about the relevance of INSPIRE research questions. They reported difficulties navigating the virtual research platform and the need for making survey participation less cognitively demanding. They sought more regular feedback on study findings.<h4>Conclusions</h4>Our findings offered insights into incorporating decentralized participatory methods in longitudinal research, strengthening reciprocal research communications, making virtual research platforms user-friendly, and employing strategies to reduce participants' cognitive burden in research.<h4>Policy implications</h4>Longitudinal studies should focus on optimizing these aspects of participant engagement to produce rigorous findings that inform policy and practice on lasting effects of COVID-19 including Long COVID.
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spelling doaj-art-0bd205fd22ff4125bdf90ec765b8038e2025-08-20T02:47:38ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01207e032594810.1371/journal.pone.0325948Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.Kris Pui Kwan MaTracy StoberMichael GottliebRachel E GeyerKristin RisingSharon SaydahMichelle SantangeloKristyn GatlingDylan GrauRalph C WangJuan Carlos MontoyAhamed IdrisSamuel MacDonaldMandy J HillRyan HuebingerMaria G PradoNicole L GentileErica SpatzCaitlin MalikiJocelyn DorneyJoann G ElmoreMichelle L'HommedieuRobert A WeinsteinArjun K VenkateshKari A StephensINSPIRE Group<h4>Objective</h4>To examine participants' motivations and their experiences throughout a decentralized, longitudinal COVID-19 study in the U.S.<h4>Methods</h4>We recruited 355 participants from the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE) between November 2022 - March 2023 to answer five qualitative survey questions anonymously. We used an inductive content analysis approach to analyze the data.<h4>Results</h4>We identified five key themes from the analysis, which reflected participants' a) motivations to join the study, b) study benefits, c) perceptions of survey questions, d) experiences with the research process, and e) preferences for disseminating research findings. Participants were motivated to learn with researchers about COVID-19. They expressed divided opinions about the relevance of INSPIRE research questions. They reported difficulties navigating the virtual research platform and the need for making survey participation less cognitively demanding. They sought more regular feedback on study findings.<h4>Conclusions</h4>Our findings offered insights into incorporating decentralized participatory methods in longitudinal research, strengthening reciprocal research communications, making virtual research platforms user-friendly, and employing strategies to reduce participants' cognitive burden in research.<h4>Policy implications</h4>Longitudinal studies should focus on optimizing these aspects of participant engagement to produce rigorous findings that inform policy and practice on lasting effects of COVID-19 including Long COVID.https://doi.org/10.1371/journal.pone.0325948
spellingShingle Kris Pui Kwan Ma
Tracy Stober
Michael Gottlieb
Rachel E Geyer
Kristin Rising
Sharon Saydah
Michelle Santangelo
Kristyn Gatling
Dylan Grau
Ralph C Wang
Juan Carlos Montoy
Ahamed Idris
Samuel MacDonald
Mandy J Hill
Ryan Huebinger
Maria G Prado
Nicole L Gentile
Erica Spatz
Caitlin Maliki
Jocelyn Dorney
Joann G Elmore
Michelle L'Hommedieu
Robert A Weinstein
Arjun K Venkatesh
Kari A Stephens
INSPIRE Group
Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.
PLoS ONE
title Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.
title_full Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.
title_fullStr Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.
title_full_unstemmed Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.
title_short Participant engagement in a national longitudinal study of COVID-19: Insights from the INSPIRE study.
title_sort participant engagement in a national longitudinal study of covid 19 insights from the inspire study
url https://doi.org/10.1371/journal.pone.0325948
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