eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma

eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma

Background Immune checkpoint blockade (ICB) targeting programmed death ligand-1 (PD-L1)/programmed cell death protein-1 (PD-1) pathway has become an attractive strategy for cancer treatment; however, unsatisfactory efficacy has limited its clinical benefits. Therefore, a more comprehensive understan...

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Bibliographic Details
Main Authors: Jianxun Song, Xiang Chen, Ying Wen, Mingzhu Yin, Yan Cheng, Wenjun Yi, Xingcong Ren, Xisha Chen, Kuansong Wang, Shilong Jiang, Hongyin Sun, Xuanling Che, Minghui Zhang, Jiaying He, Mengting Liao, Xiangling Li, Xiaoming Zhou, Jinming Yang
Format: Article
Language:English
Published: BMJ Publishing Group 2022-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/3/e004026.full
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