The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography
ObjectiveThis study explored the associations among muscle strength, inhibitory control, and cognitive function in older adults with cognitive impairment, focusing on related EEG changes.MethodsAmong 247 adults aged 70 and above, 120 with cognitive impairment were included. Assessments included the...
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2025.1574275/full |
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| author | Mi Hu Xing Wang |
| author_facet | Mi Hu Xing Wang |
| author_sort | Mi Hu |
| collection | DOAJ |
| description | ObjectiveThis study explored the associations among muscle strength, inhibitory control, and cognitive function in older adults with cognitive impairment, focusing on related EEG changes.MethodsAmong 247 adults aged 70 and above, 120 with cognitive impairment were included. Assessments included the Montreal Cognitive Assessment (MoCA), Stroop task, grip strength, and resting-state EEG.ResultsInhibitory control was significantly related to cognitive function: accuracy in congruent (r = 0.599, p < 0.001) and incongruent (r = 0.474, p < 0.001) conditions correlated positively with MoCA scores, while response times in both conditions showed negative correlations (r = –0.475 and –0.354, respectively, p < 0.001). EEG alpha1 (C3, P3, F7), alpha2 (P3, F8), and beta1 (P3, F7) power were significantly associated with both cognitive and inhibitory performance. Muscle strength was significantly positively correlated with specific EEG indicators, particularly alpha1 power at C4 (r = 0.212, p < 0.05), O2 (r = 0.204, p < 0.05), F8 (r = 0.225, p < 0.05), and T6 (r = 0.206, p < 0.05), as well as alpha2 power at C3 (r = 0.216, p < 0.05), P3 (r = 0.222, p < 0.05), P4 (r = 0.268, p < 0.001), F8 (r = 0.284, p < 0.001), and T5 (r = 0.218, p < 0.05).ConclusionMuscle strength may support cognitive and inhibitory function by influencing specific EEG activities. These findings highlight the neurophysiological links among muscle strength, cognition, and brain activity, offering potential biomarkers for early detection and intervention in cognitive decline. |
| format | Article |
| id | doaj-art-0bcde21f39dc4afa92aa9e2a0e5a470e |
| institution | OA Journals |
| issn | 1663-4365 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj-art-0bcde21f39dc4afa92aa9e2a0e5a470e2025-08-20T02:36:08ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652025-06-011710.3389/fnagi.2025.15742751574275The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalographyMi Hu0Xing Wang1Department of Physical Education, East China University of Political Science and Law, Shanghai, ChinaSchool of Physical Education, Shanghai University of Sport, Shanghai, ChinaObjectiveThis study explored the associations among muscle strength, inhibitory control, and cognitive function in older adults with cognitive impairment, focusing on related EEG changes.MethodsAmong 247 adults aged 70 and above, 120 with cognitive impairment were included. Assessments included the Montreal Cognitive Assessment (MoCA), Stroop task, grip strength, and resting-state EEG.ResultsInhibitory control was significantly related to cognitive function: accuracy in congruent (r = 0.599, p < 0.001) and incongruent (r = 0.474, p < 0.001) conditions correlated positively with MoCA scores, while response times in both conditions showed negative correlations (r = –0.475 and –0.354, respectively, p < 0.001). EEG alpha1 (C3, P3, F7), alpha2 (P3, F8), and beta1 (P3, F7) power were significantly associated with both cognitive and inhibitory performance. Muscle strength was significantly positively correlated with specific EEG indicators, particularly alpha1 power at C4 (r = 0.212, p < 0.05), O2 (r = 0.204, p < 0.05), F8 (r = 0.225, p < 0.05), and T6 (r = 0.206, p < 0.05), as well as alpha2 power at C3 (r = 0.216, p < 0.05), P3 (r = 0.222, p < 0.05), P4 (r = 0.268, p < 0.001), F8 (r = 0.284, p < 0.001), and T5 (r = 0.218, p < 0.05).ConclusionMuscle strength may support cognitive and inhibitory function by influencing specific EEG activities. These findings highlight the neurophysiological links among muscle strength, cognition, and brain activity, offering potential biomarkers for early detection and intervention in cognitive decline.https://www.frontiersin.org/articles/10.3389/fnagi.2025.1574275/fullinhibitory functioncognitive functionmuscle strengthEEGolder adult |
| spellingShingle | Mi Hu Xing Wang The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography Frontiers in Aging Neuroscience inhibitory function cognitive function muscle strength EEG older adult |
| title | The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography |
| title_full | The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography |
| title_fullStr | The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography |
| title_full_unstemmed | The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography |
| title_short | The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: evidence from resting-state electroencephalography |
| title_sort | correlation between muscle strength inhibitory function and cognitive function in older adults with cognitive impairment evidence from resting state electroencephalography |
| topic | inhibitory function cognitive function muscle strength EEG older adult |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2025.1574275/full |
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