ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Often local inflammation develops into systemic one with total inflammatory response of endotheliocytes, plasma and cellular blood factors, connective tissue, and at the final stages it is manifested through microcirculatory disorders in vital organs and tissues. At present two aspects are being inv...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2017-06-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1015 |
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| author | V. A. Nikitin L. V. Vаsilievа E. M. Tolstykh A. S. Nogovitsynа |
| author_facet | V. A. Nikitin L. V. Vаsilievа E. M. Tolstykh A. S. Nogovitsynа |
| author_sort | V. A. Nikitin |
| collection | DOAJ |
| description | Often local inflammation develops into systemic one with total inflammatory response of endotheliocytes, plasma and cellular blood factors, connective tissue, and at the final stages it is manifested through microcirculatory disorders in vital organs and tissues. At present two aspects are being investigated related to systemic inflammation in chronic obstructive pulmonary disease (COPD). Firstly, it is the evaluation of inflammatory load through testing the level of inflammation markers in blood. Secondly, now it is generally recognized that a number of typical extrapulmonary disorders and concurrent diseases develops in COPD patients. Regardless of these general pathogenic mechanisms, the one thing is clear: cardiovascular diseases, body weight loss, osteoporosis and a number of other extrapulmonary manifestations of COPD are related to systematic inflammatory response. |
| format | Article |
| id | doaj-art-0bc5b821f98c408b80a97c1612b48d45 |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2017-06-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-0bc5b821f98c408b80a97c1612b48d452025-08-20T02:16:01ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062017-06-01956616610.21292/2075-1230-2017-95-6-61-661015ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASEV. A. Nikitin0L. V. Vаsilievа1E. M. Tolstykh2A. S. Nogovitsynа3Voronezh State Medical academy named After N. N. BurdenkoVoronezh State Medical academy named After N. N. BurdenkoVoronezh State Medical academy named After N. N. Burdenkolipetsk Municipal Polyclinic no. 7Often local inflammation develops into systemic one with total inflammatory response of endotheliocytes, plasma and cellular blood factors, connective tissue, and at the final stages it is manifested through microcirculatory disorders in vital organs and tissues. At present two aspects are being investigated related to systemic inflammation in chronic obstructive pulmonary disease (COPD). Firstly, it is the evaluation of inflammatory load through testing the level of inflammation markers in blood. Secondly, now it is generally recognized that a number of typical extrapulmonary disorders and concurrent diseases develops in COPD patients. Regardless of these general pathogenic mechanisms, the one thing is clear: cardiovascular diseases, body weight loss, osteoporosis and a number of other extrapulmonary manifestations of COPD are related to systematic inflammatory response.https://www.tibl-journal.com/jour/article/view/1015systemic inflammationchronic obstructive pulmonary disease |
| spellingShingle | V. A. Nikitin L. V. Vаsilievа E. M. Tolstykh A. S. Nogovitsynа ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE Туберкулез и болезни лёгких systemic inflammation chronic obstructive pulmonary disease |
| title | ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE |
| title_full | ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE |
| title_fullStr | ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE |
| title_full_unstemmed | ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE |
| title_short | ROLE OF SYSTEMATIC INFLAMMATION IN THE DEVELOPMENT OF COMORBIDITY IN CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE |
| title_sort | role of systematic inflammation in the development of comorbidity in case of chronic obstructive pulmonary disease |
| topic | systemic inflammation chronic obstructive pulmonary disease |
| url | https://www.tibl-journal.com/jour/article/view/1015 |
| work_keys_str_mv | AT vanikitin roleofsystematicinflammationinthedevelopmentofcomorbidityincaseofchronicobstructivepulmonarydisease AT lvvasilieva roleofsystematicinflammationinthedevelopmentofcomorbidityincaseofchronicobstructivepulmonarydisease AT emtolstykh roleofsystematicinflammationinthedevelopmentofcomorbidityincaseofchronicobstructivepulmonarydisease AT asnogovitsyna roleofsystematicinflammationinthedevelopmentofcomorbidityincaseofchronicobstructivepulmonarydisease |