A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients

Objective. Evaluate the prevalence and outcomes of urinary tract infection (UTI) among renal transplant recipients. Methods. A secondary analysis of the Nationwide Inpatient Sample 2009–2011 was conducted. Survey-weighted multivariable regression analyses were used to examine the impact of UTI on tr...

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Main Authors: Benjamin J. Becerra, Monideepa B. Becerra, Nasia Safdar
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2015/854640
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author Benjamin J. Becerra
Monideepa B. Becerra
Nasia Safdar
author_facet Benjamin J. Becerra
Monideepa B. Becerra
Nasia Safdar
author_sort Benjamin J. Becerra
collection DOAJ
description Objective. Evaluate the prevalence and outcomes of urinary tract infection (UTI) among renal transplant recipients. Methods. A secondary analysis of the Nationwide Inpatient Sample 2009–2011 was conducted. Survey-weighted multivariable regression analyses were used to examine the impact of UTI on transplant complications, total charges, and length of stay. Results. A total of 1,044 renal transplant recipients, representing a population estimate of 49,862, were included in the study. UTI was most common in transplant recipients with hypertension (53%) and prevalence was noted to be 28.2 and 65.9 cases per 1,000 for men and women, respectively. UTI increased the likelihood of transplant complications (182% for men, 169% for women). Total charges were 28% higher among men as compared to 22% among women with UTI. Such infection also increased the length of stay by 87% among men and 74% among women. Discussion. UTI in renal transplant recipients was associated with prolonged length of stay, total charges, and increased odds of transplant complications. Interventions to prevent UTI among such patients should be a priority area for future research and practice.
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spelling doaj-art-0bc26ef62bbb431fa639e0b58ec565a42025-02-03T05:58:45ZengWileyJournal of Transplantation2090-00072090-00152015-01-01201510.1155/2015/854640854640A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant RecipientsBenjamin J. Becerra0Monideepa B. Becerra1Nasia Safdar2School of Public Health, Loma Linda University, Loma Linda, CA 92350, USAWilliam S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USAWilliam S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USAObjective. Evaluate the prevalence and outcomes of urinary tract infection (UTI) among renal transplant recipients. Methods. A secondary analysis of the Nationwide Inpatient Sample 2009–2011 was conducted. Survey-weighted multivariable regression analyses were used to examine the impact of UTI on transplant complications, total charges, and length of stay. Results. A total of 1,044 renal transplant recipients, representing a population estimate of 49,862, were included in the study. UTI was most common in transplant recipients with hypertension (53%) and prevalence was noted to be 28.2 and 65.9 cases per 1,000 for men and women, respectively. UTI increased the likelihood of transplant complications (182% for men, 169% for women). Total charges were 28% higher among men as compared to 22% among women with UTI. Such infection also increased the length of stay by 87% among men and 74% among women. Discussion. UTI in renal transplant recipients was associated with prolonged length of stay, total charges, and increased odds of transplant complications. Interventions to prevent UTI among such patients should be a priority area for future research and practice.http://dx.doi.org/10.1155/2015/854640
spellingShingle Benjamin J. Becerra
Monideepa B. Becerra
Nasia Safdar
A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients
Journal of Transplantation
title A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients
title_full A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients
title_fullStr A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients
title_full_unstemmed A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients
title_short A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients
title_sort nationwide assessment of the burden of urinary tract infection among renal transplant recipients
url http://dx.doi.org/10.1155/2015/854640
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