Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute Toxicity

Biocides are often used in various industries and applications to control microbial growth and prevent the deterioration of materials, and they often have the ability to target a wide range of microorganisms rather than being specific to one type. They are designed to be highly effective at killing...

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Main Authors: Assem Issayeva, Saule Aidarova, Galiya Madybekova, Seitzhan Turganbay, Alpamys Babayev, Miras Issakhov, Altynay Sharipova, Reinhard Miller, Botagoz Mutaliyeva
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Colloids and Interfaces
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Online Access:https://www.mdpi.com/2504-5377/9/1/2
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author Assem Issayeva
Saule Aidarova
Galiya Madybekova
Seitzhan Turganbay
Alpamys Babayev
Miras Issakhov
Altynay Sharipova
Reinhard Miller
Botagoz Mutaliyeva
author_facet Assem Issayeva
Saule Aidarova
Galiya Madybekova
Seitzhan Turganbay
Alpamys Babayev
Miras Issakhov
Altynay Sharipova
Reinhard Miller
Botagoz Mutaliyeva
author_sort Assem Issayeva
collection DOAJ
description Biocides are often used in various industries and applications to control microbial growth and prevent the deterioration of materials, and they often have the ability to target a wide range of microorganisms rather than being specific to one type. They are designed to be highly effective at killing or inhibiting the growth of microorganisms and some biocides have residual activity, meaning they remain active for a period of time after application, providing longer-term protection. Biocides need to be compatible with the materials and surfaces they are applied to without causing damage or adverse effects, and they should remain stable under various environmental conditions, such as temperature and pH, to maintain their efficacy over time. In this study, microcapsules incorporating the biocide 4,5-dichloro-2-n-octyl-4-isotriazolin-3-one (DCOIT) were synthesized, and their effectiveness was evaluated. The investigation focused on several aspects, including colloidal chemical properties such as interfacial tension at pH values of 3, 7, and 9, as well as the size, ζ-potential, and morphology of the microcapsules. To validate the microcapsule production, elemental analysis was performed, and the effects on wettability and toxicological properties were assessed within the DCOIT + trimethoxysilyl propylmethacrylate/silicon dioxide nanoparticle system. Interfacial tension kinetics were measured using the PAT-1 tensiometer. The microcapsules exhibited an average diameter of 146 ± 1 nm following emulsification, with a ζ-potential of −50.2 ± 1 mV, as determined by the Malvern Zetasizer Nano Z. The morphology of the microcapsules was characterized using the SEM Controller 1550. Elemental composition was analyzed via energy-dispersive X-ray microanalysis (EDAX). The study concluded that the DCOIT biocide, when incorporated in the TPM/SiO<sub>2</sub> system, demonstrated non-toxic properties.
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spelling doaj-art-0bc05d671bee489fa0cc02fa158895a22025-08-20T03:11:21ZengMDPI AGColloids and Interfaces2504-53772024-12-0191210.3390/colloids9010002Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute ToxicityAssem Issayeva0Saule Aidarova1Galiya Madybekova2Seitzhan Turganbay3Alpamys Babayev4Miras Issakhov5Altynay Sharipova6Reinhard Miller7Botagoz Mutaliyeva8“One Belt, one Road” Petroleum Engineering Institute, Kazakh-British Technical University, Almaty 050000, Kazakhstan“One Belt, one Road” Petroleum Engineering Institute, Kazakh-British Technical University, Almaty 050000, KazakhstanChemistry Department, O. Zhanibekov South-Kazakhstan Pedagogical University, Shymkent 160000, Kazakhstan“One Belt, one Road” Petroleum Engineering Institute, Kazakh-British Technical University, Almaty 050000, Kazakhstan“One Belt, one Road” Petroleum Engineering Institute, Kazakh-British Technical University, Almaty 050000, Kazakhstan“One Belt, one Road” Petroleum Engineering Institute, Kazakh-British Technical University, Almaty 050000, KazakhstanMining and Metallurgical Institute, Satbayev University, Almaty 050013, KazakhstanInstitute for Condensed Matter Physics, Technical University of Darmstadt, 64289 Darmstadt, GermanyBiotechnology Department, M. Auezov South-Kazakhstan University, Shymkent 160000, KazakhstanBiocides are often used in various industries and applications to control microbial growth and prevent the deterioration of materials, and they often have the ability to target a wide range of microorganisms rather than being specific to one type. They are designed to be highly effective at killing or inhibiting the growth of microorganisms and some biocides have residual activity, meaning they remain active for a period of time after application, providing longer-term protection. Biocides need to be compatible with the materials and surfaces they are applied to without causing damage or adverse effects, and they should remain stable under various environmental conditions, such as temperature and pH, to maintain their efficacy over time. In this study, microcapsules incorporating the biocide 4,5-dichloro-2-n-octyl-4-isotriazolin-3-one (DCOIT) were synthesized, and their effectiveness was evaluated. The investigation focused on several aspects, including colloidal chemical properties such as interfacial tension at pH values of 3, 7, and 9, as well as the size, ζ-potential, and morphology of the microcapsules. To validate the microcapsule production, elemental analysis was performed, and the effects on wettability and toxicological properties were assessed within the DCOIT + trimethoxysilyl propylmethacrylate/silicon dioxide nanoparticle system. Interfacial tension kinetics were measured using the PAT-1 tensiometer. The microcapsules exhibited an average diameter of 146 ± 1 nm following emulsification, with a ζ-potential of −50.2 ± 1 mV, as determined by the Malvern Zetasizer Nano Z. The morphology of the microcapsules was characterized using the SEM Controller 1550. Elemental composition was analyzed via energy-dispersive X-ray microanalysis (EDAX). The study concluded that the DCOIT biocide, when incorporated in the TPM/SiO<sub>2</sub> system, demonstrated non-toxic properties.https://www.mdpi.com/2504-5377/9/1/2microencapsulationbiocidenanoparticlemicrocapsulesinterfacial tensionacute toxicity
spellingShingle Assem Issayeva
Saule Aidarova
Galiya Madybekova
Seitzhan Turganbay
Alpamys Babayev
Miras Issakhov
Altynay Sharipova
Reinhard Miller
Botagoz Mutaliyeva
Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute Toxicity
Colloids and Interfaces
microencapsulation
biocide
nanoparticle
microcapsules
interfacial tension
acute toxicity
title Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute Toxicity
title_full Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute Toxicity
title_fullStr Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute Toxicity
title_full_unstemmed Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute Toxicity
title_short Microencapsulation Efficiency of DCOIT Biocide in the TPM/SiO<sub>2</sub> System and a Study of Their Acute Toxicity
title_sort microencapsulation efficiency of dcoit biocide in the tpm sio sub 2 sub system and a study of their acute toxicity
topic microencapsulation
biocide
nanoparticle
microcapsules
interfacial tension
acute toxicity
url https://www.mdpi.com/2504-5377/9/1/2
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