Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort study
The present study evaluated the real-world effectiveness of influenza and pneumococcal dual-vaccination among Chinese elderly, the evidence on which was absent. Outpatient and inpatient claims databases from Jan 1, 2015 to Apr 1, 2017 of persons at least 60 years old in Shenzhen, China were merged w...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-01-01
|
| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2020.1854624 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850186988086362112 |
|---|---|
| author | Yawen Jiang Zhaojia Ye Daqin Chen Yuelong Shu |
| author_facet | Yawen Jiang Zhaojia Ye Daqin Chen Yuelong Shu |
| author_sort | Yawen Jiang |
| collection | DOAJ |
| description | The present study evaluated the real-world effectiveness of influenza and pneumococcal dual-vaccination among Chinese elderly, the evidence on which was absent. Outpatient and inpatient claims databases from Jan 1, 2015 to Apr 1, 2017 of persons at least 60 years old in Shenzhen, China were merged with electronic records of influenza vaccines and 23-valent pneumococcal polysaccharide vaccines (PPSV23) from Oct 1, 2016 - May 31, 2017. Individuals who were vaccinated with influenza between Nov 1 and Dec 31, 2016 and received PPSV23 30 days within the date of influenza vaccination were defined as the vaccinated group. A control group consisted of individuals that received neither of the vaccines was constructed by matching on year of birth, sex, and district. The two outcomes were all-cause and acute respiratory hospitalizations. Difference-in-difference (DiD) logistic regressions that were proceeded with an entropy balancing (EB) process were used to analyse the effectiveness of dual-vaccination. A total of 48,116 eligible individuals were identified in the vaccinated group, which were matched by 93,692 individuals in the control group. The EB-DiD analyses estimated that dual-vaccination was associated with lower short-term risks of all-cause (odds ratio: 0.59, CI: 0.55-0.63) and acute respiratory (odds ratio: 0.49, CI: 0.41-0.59) hospitalizations. |
| format | Article |
| id | doaj-art-0bb6e310ecec446e94ed02a7a7d8ecd5 |
| institution | OA Journals |
| issn | 2222-1751 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-0bb6e310ecec446e94ed02a7a7d8ecd52025-08-20T02:16:13ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512020-01-01912578258710.1080/22221751.2020.1854624Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort studyYawen Jiang0Zhaojia Ye1Daqin Chen2Yuelong Shu3School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, People’s Republic of ChinaShenzhen Center for Disease Control and Prevention, Shenzhen, People’s Republic of ChinaSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, People’s Republic of ChinaSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, People’s Republic of ChinaThe present study evaluated the real-world effectiveness of influenza and pneumococcal dual-vaccination among Chinese elderly, the evidence on which was absent. Outpatient and inpatient claims databases from Jan 1, 2015 to Apr 1, 2017 of persons at least 60 years old in Shenzhen, China were merged with electronic records of influenza vaccines and 23-valent pneumococcal polysaccharide vaccines (PPSV23) from Oct 1, 2016 - May 31, 2017. Individuals who were vaccinated with influenza between Nov 1 and Dec 31, 2016 and received PPSV23 30 days within the date of influenza vaccination were defined as the vaccinated group. A control group consisted of individuals that received neither of the vaccines was constructed by matching on year of birth, sex, and district. The two outcomes were all-cause and acute respiratory hospitalizations. Difference-in-difference (DiD) logistic regressions that were proceeded with an entropy balancing (EB) process were used to analyse the effectiveness of dual-vaccination. A total of 48,116 eligible individuals were identified in the vaccinated group, which were matched by 93,692 individuals in the control group. The EB-DiD analyses estimated that dual-vaccination was associated with lower short-term risks of all-cause (odds ratio: 0.59, CI: 0.55-0.63) and acute respiratory (odds ratio: 0.49, CI: 0.41-0.59) hospitalizations.https://www.tandfonline.com/doi/10.1080/22221751.2020.1854624Influenzapneumoniavaccineelderlyriskhospitalization |
| spellingShingle | Yawen Jiang Zhaojia Ye Daqin Chen Yuelong Shu Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort study Emerging Microbes and Infections Influenza pneumonia vaccine elderly risk hospitalization |
| title | Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort study |
| title_full | Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort study |
| title_fullStr | Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort study |
| title_full_unstemmed | Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort study |
| title_short | Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort study |
| title_sort | dual influenza and pneumococcal vaccination was associated with lower short term risks of all cause and acute respiratory hospitalizations among the elderly in shenzhen china a retrospective cohort study |
| topic | Influenza pneumonia vaccine elderly risk hospitalization |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2020.1854624 |
| work_keys_str_mv | AT yawenjiang dualinfluenzaandpneumococcalvaccinationwasassociatedwithlowershorttermrisksofallcauseandacuterespiratoryhospitalizationsamongtheelderlyinshenzhenchinaaretrospectivecohortstudy AT zhaojiaye dualinfluenzaandpneumococcalvaccinationwasassociatedwithlowershorttermrisksofallcauseandacuterespiratoryhospitalizationsamongtheelderlyinshenzhenchinaaretrospectivecohortstudy AT daqinchen dualinfluenzaandpneumococcalvaccinationwasassociatedwithlowershorttermrisksofallcauseandacuterespiratoryhospitalizationsamongtheelderlyinshenzhenchinaaretrospectivecohortstudy AT yuelongshu dualinfluenzaandpneumococcalvaccinationwasassociatedwithlowershorttermrisksofallcauseandacuterespiratoryhospitalizationsamongtheelderlyinshenzhenchinaaretrospectivecohortstudy |