Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis
Avascular osteonecrosis (AON) is a common condition that most often affects people of working age (20–60 years). The disease leads to rapid destruction and collapse of the subchondral bone with subsequent development of secondary osteoarthritis of the affected joint. The current data on laboratory a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2025-02-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/1707 |
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| author | V. E. Bialik M. A. Makarov E. I. Bialik S. A. Makarov A. E. Karateev A. M. Lila V. A. Nesterenko A. A. Bialik D. V. Kapitonov A. I. Gorelova |
| author_facet | V. E. Bialik M. A. Makarov E. I. Bialik S. A. Makarov A. E. Karateev A. M. Lila V. A. Nesterenko A. A. Bialik D. V. Kapitonov A. I. Gorelova |
| author_sort | V. E. Bialik |
| collection | DOAJ |
| description | Avascular osteonecrosis (AON) is a common condition that most often affects people of working age (20–60 years). The disease leads to rapid destruction and collapse of the subchondral bone with subsequent development of secondary osteoarthritis of the affected joint. The current data on laboratory abnormalities in AON are presented. Biomarkers directly related to the development and progression of AON are described in detail. Ideas for future research are formulated to improve the detection and treatment of the disease. |
| format | Article |
| id | doaj-art-0bb62d5d02604618bccd27c03028a6ad |
| institution | DOAJ |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2025-02-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-0bb62d5d02604618bccd27c03028a6ad2025-08-20T03:01:21ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2025-02-01191839010.14412/1996-7012-2025-1-83-902760Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosisV. E. Bialik0M. A. Makarov1E. I. Bialik2S. A. Makarov3A. E. Karateev4A. M. Lila5V. A. Nesterenko6A. A. Bialik7D. V. Kapitonov8A. I. Gorelova9V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyAvascular osteonecrosis (AON) is a common condition that most often affects people of working age (20–60 years). The disease leads to rapid destruction and collapse of the subchondral bone with subsequent development of secondary osteoarthritis of the affected joint. The current data on laboratory abnormalities in AON are presented. Biomarkers directly related to the development and progression of AON are described in detail. Ideas for future research are formulated to improve the detection and treatment of the disease.https://mrj.ima-press.net/mrj/article/view/1707avascular osteonecrosisthrombophiliahypofibrinolysisranklosteoprotegerinadiponectinamyloid aα2-macroglobulin |
| spellingShingle | V. E. Bialik M. A. Makarov E. I. Bialik S. A. Makarov A. E. Karateev A. M. Lila V. A. Nesterenko A. A. Bialik D. V. Kapitonov A. I. Gorelova Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis Современная ревматология avascular osteonecrosis thrombophilia hypofibrinolysis rankl osteoprotegerin adiponectin amyloid a α2-macroglobulin |
| title | Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis |
| title_full | Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis |
| title_fullStr | Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis |
| title_full_unstemmed | Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis |
| title_short | Known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis |
| title_sort | known laboratory abnormalities and potential targets for the conservative treatment of avascular osteonecrosis |
| topic | avascular osteonecrosis thrombophilia hypofibrinolysis rankl osteoprotegerin adiponectin amyloid a α2-macroglobulin |
| url | https://mrj.ima-press.net/mrj/article/view/1707 |
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