Artificial intelligence supporting cancer patients across Europe-The ASCAPE project.
<h4>Introduction</h4>Breast and prostate cancer survivors can experience impaired quality of life (QoL) in several QoL domains. The current strategy to support cancer survivors with impaired QoL is suboptimal, leading to unmet patient needs. ASCAPE aims to provide personalized- and artif...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0265127&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849245767653392384 |
|---|---|
| author | Lazaros Tzelves Ioannis Manolitsis Ioannis Varkarakis Mirjana Ivanovic Miltiadis Kokkonidis Cristina Sabater Useros Thanos Kosmidis Montserrat Muñoz Imma Grau Manos Athanatos Anamaria Vizitiu Konstantinos Lampropoulos Tzortzia Koutsouri Dimitra Stefanatou Konstantinos Perrakis Christina Stratigaki Serge Autexier Paris Kosmidis Antonis Valachis |
| author_facet | Lazaros Tzelves Ioannis Manolitsis Ioannis Varkarakis Mirjana Ivanovic Miltiadis Kokkonidis Cristina Sabater Useros Thanos Kosmidis Montserrat Muñoz Imma Grau Manos Athanatos Anamaria Vizitiu Konstantinos Lampropoulos Tzortzia Koutsouri Dimitra Stefanatou Konstantinos Perrakis Christina Stratigaki Serge Autexier Paris Kosmidis Antonis Valachis |
| author_sort | Lazaros Tzelves |
| collection | DOAJ |
| description | <h4>Introduction</h4>Breast and prostate cancer survivors can experience impaired quality of life (QoL) in several QoL domains. The current strategy to support cancer survivors with impaired QoL is suboptimal, leading to unmet patient needs. ASCAPE aims to provide personalized- and artificial intelligence (AI)-based predictions for QoL issues in breast- and prostate cancer patients as well as to suggest potential interventions to their physicians to offer a more modern and holistic approach on cancer rehabilitation.<h4>Methods and analyses</h4>An AI-based platform aiming to predict QoL issues and suggest appropriate interventions to clinicians will be built based on patient data gathered through medical records, questionnaires, apps, and wearables. This platform will be prospectively evaluated through a longitudinal study where breast and prostate cancer survivors from four different study sites across the Europe will be enrolled. The evaluation of the AI-based follow-up strategy through the ASCAPE platform will be based on patients' experience, engagement, and potential improvement in QoL during the study as well as on clinicians' view on how ASCAPE platform impacts their clinical practice and doctor-patient relationship, and their experience in using the platform.<h4>Ethics and dissemination</h4>ASCAPE is the first research project that will prospectively investigate an AI-based approach for an individualized follow-up strategy for patients with breast- or prostate cancer focusing on patients' QoL issues. ASCAPE represents a paradigm shift both in terms of a more individualized approach for follow-up based on QoL issues, which is an unmet need for cancer survivors, and in terms of how to use Big Data in cancer care through democratizing the knowledge and the access to AI and Big Data related innovations.<h4>Trial registration</h4>Trial Registration on clinicaltrials.gov: NCT04879563. |
| format | Article |
| id | doaj-art-0bb5b49ef4c844c69030a04fdd325f53 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-0bb5b49ef4c844c69030a04fdd325f532025-08-20T03:58:41ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01174e026512710.1371/journal.pone.0265127Artificial intelligence supporting cancer patients across Europe-The ASCAPE project.Lazaros TzelvesIoannis ManolitsisIoannis VarkarakisMirjana IvanovicMiltiadis KokkonidisCristina Sabater UserosThanos KosmidisMontserrat MuñozImma GrauManos AthanatosAnamaria VizitiuKonstantinos LampropoulosTzortzia KoutsouriDimitra StefanatouKonstantinos PerrakisChristina StratigakiSerge AutexierParis KosmidisAntonis Valachis<h4>Introduction</h4>Breast and prostate cancer survivors can experience impaired quality of life (QoL) in several QoL domains. The current strategy to support cancer survivors with impaired QoL is suboptimal, leading to unmet patient needs. ASCAPE aims to provide personalized- and artificial intelligence (AI)-based predictions for QoL issues in breast- and prostate cancer patients as well as to suggest potential interventions to their physicians to offer a more modern and holistic approach on cancer rehabilitation.<h4>Methods and analyses</h4>An AI-based platform aiming to predict QoL issues and suggest appropriate interventions to clinicians will be built based on patient data gathered through medical records, questionnaires, apps, and wearables. This platform will be prospectively evaluated through a longitudinal study where breast and prostate cancer survivors from four different study sites across the Europe will be enrolled. The evaluation of the AI-based follow-up strategy through the ASCAPE platform will be based on patients' experience, engagement, and potential improvement in QoL during the study as well as on clinicians' view on how ASCAPE platform impacts their clinical practice and doctor-patient relationship, and their experience in using the platform.<h4>Ethics and dissemination</h4>ASCAPE is the first research project that will prospectively investigate an AI-based approach for an individualized follow-up strategy for patients with breast- or prostate cancer focusing on patients' QoL issues. ASCAPE represents a paradigm shift both in terms of a more individualized approach for follow-up based on QoL issues, which is an unmet need for cancer survivors, and in terms of how to use Big Data in cancer care through democratizing the knowledge and the access to AI and Big Data related innovations.<h4>Trial registration</h4>Trial Registration on clinicaltrials.gov: NCT04879563.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0265127&type=printable |
| spellingShingle | Lazaros Tzelves Ioannis Manolitsis Ioannis Varkarakis Mirjana Ivanovic Miltiadis Kokkonidis Cristina Sabater Useros Thanos Kosmidis Montserrat Muñoz Imma Grau Manos Athanatos Anamaria Vizitiu Konstantinos Lampropoulos Tzortzia Koutsouri Dimitra Stefanatou Konstantinos Perrakis Christina Stratigaki Serge Autexier Paris Kosmidis Antonis Valachis Artificial intelligence supporting cancer patients across Europe-The ASCAPE project. PLoS ONE |
| title | Artificial intelligence supporting cancer patients across Europe-The ASCAPE project. |
| title_full | Artificial intelligence supporting cancer patients across Europe-The ASCAPE project. |
| title_fullStr | Artificial intelligence supporting cancer patients across Europe-The ASCAPE project. |
| title_full_unstemmed | Artificial intelligence supporting cancer patients across Europe-The ASCAPE project. |
| title_short | Artificial intelligence supporting cancer patients across Europe-The ASCAPE project. |
| title_sort | artificial intelligence supporting cancer patients across europe the ascape project |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0265127&type=printable |
| work_keys_str_mv | AT lazarostzelves artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT ioannismanolitsis artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT ioannisvarkarakis artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT mirjanaivanovic artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT miltiadiskokkonidis artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT cristinasabateruseros artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT thanoskosmidis artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT montserratmunoz artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT immagrau artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT manosathanatos artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT anamariavizitiu artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT konstantinoslampropoulos artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT tzortziakoutsouri artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT dimitrastefanatou artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT konstantinosperrakis artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT christinastratigaki artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT sergeautexier artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT pariskosmidis artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject AT antonisvalachis artificialintelligencesupportingcancerpatientsacrosseuropetheascapeproject |