In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite Scaffolds

The present work reported the preparation of biocomposites based on poly(3-hydroxybutyrate) (PHB), plasticizer, and bacterial cellulose (BC) by melt processing and their testing by means of thermal properties (DSC), water absorption, and in vitro degradation. The surface of the biocomposites was ana...

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Main Authors: Maria Râpă, Cătălin Zaharia, Paul Octavian Stănescu, Angela Cășărică, Ecaterina Matei, Andra Mihaela Predescu, Mircea Cristian Pantilimon, Ruxandra Vidu, Cristian Predescu, Horia Cioflan
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2021/3820364
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author Maria Râpă
Cătălin Zaharia
Paul Octavian Stănescu
Angela Cășărică
Ecaterina Matei
Andra Mihaela Predescu
Mircea Cristian Pantilimon
Ruxandra Vidu
Cristian Predescu
Horia Cioflan
author_facet Maria Râpă
Cătălin Zaharia
Paul Octavian Stănescu
Angela Cășărică
Ecaterina Matei
Andra Mihaela Predescu
Mircea Cristian Pantilimon
Ruxandra Vidu
Cristian Predescu
Horia Cioflan
author_sort Maria Râpă
collection DOAJ
description The present work reported the preparation of biocomposites based on poly(3-hydroxybutyrate) (PHB), plasticizer, and bacterial cellulose (BC) by melt processing and their testing by means of thermal properties (DSC), water absorption, and in vitro degradation. The surface of the biocomposites was analyzed via atomic force microscopy (AFM). In vitro degradation of the biocomposites was evaluated by weight loss and thermal properties (DSC) assessment after the immersion of the specimens in phosphate-buffered saline solution (PBS of pH 7.4) over 20 days. The results showed that the BC can reduce the PHB crystallinity and promote its degradation under PBS medium. Moreover, it was found that the water absorption increased as the percentage of BC increased.
format Article
id doaj-art-0ba866f962fa43f6a7d0d0764d4438c7
institution Kabale University
issn 1687-9422
1687-9430
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series International Journal of Polymer Science
spelling doaj-art-0ba866f962fa43f6a7d0d0764d4438c72025-02-03T01:25:47ZengWileyInternational Journal of Polymer Science1687-94221687-94302021-01-01202110.1155/2021/38203643820364In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite ScaffoldsMaria Râpă0Cătălin Zaharia1Paul Octavian Stănescu2Angela Cășărică3Ecaterina Matei4Andra Mihaela Predescu5Mircea Cristian Pantilimon6Ruxandra Vidu7Cristian Predescu8Horia Cioflan9University Politehnica of Bucharest, Faculty of Materials Science and Engineering, 313 Splaiul Independentei, 060042 Bucharest, RomaniaUniversity Politehnica of Bucharest, Advanced Polymer Materials Group, 1-7 Gh. Polizu Str., 011061 Bucharest, RomaniaUniversity Politehnica of Bucharest, Advanced Polymer Materials Group, 1-7 Gh. Polizu Str., 011061 Bucharest, RomaniaNational Chemical-Pharmaceutical for Research and Development Institute, Vitan Avenue, No. 112, District 3, Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Materials Science and Engineering, 313 Splaiul Independentei, 060042 Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Materials Science and Engineering, 313 Splaiul Independentei, 060042 Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Materials Science and Engineering, 313 Splaiul Independentei, 060042 Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Materials Science and Engineering, 313 Splaiul Independentei, 060042 Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Materials Science and Engineering, 313 Splaiul Independentei, 060042 Bucharest, RomaniaSanador Clinic Hospital, Sevastopol Street No. 9 Sector 1, Bucharest, RomaniaThe present work reported the preparation of biocomposites based on poly(3-hydroxybutyrate) (PHB), plasticizer, and bacterial cellulose (BC) by melt processing and their testing by means of thermal properties (DSC), water absorption, and in vitro degradation. The surface of the biocomposites was analyzed via atomic force microscopy (AFM). In vitro degradation of the biocomposites was evaluated by weight loss and thermal properties (DSC) assessment after the immersion of the specimens in phosphate-buffered saline solution (PBS of pH 7.4) over 20 days. The results showed that the BC can reduce the PHB crystallinity and promote its degradation under PBS medium. Moreover, it was found that the water absorption increased as the percentage of BC increased.http://dx.doi.org/10.1155/2021/3820364
spellingShingle Maria Râpă
Cătălin Zaharia
Paul Octavian Stănescu
Angela Cășărică
Ecaterina Matei
Andra Mihaela Predescu
Mircea Cristian Pantilimon
Ruxandra Vidu
Cristian Predescu
Horia Cioflan
In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite Scaffolds
International Journal of Polymer Science
title In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite Scaffolds
title_full In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite Scaffolds
title_fullStr In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite Scaffolds
title_full_unstemmed In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite Scaffolds
title_short In Vitro Degradation of PHB/Bacterial Cellulose Biocomposite Scaffolds
title_sort in vitro degradation of phb bacterial cellulose biocomposite scaffolds
url http://dx.doi.org/10.1155/2021/3820364
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