Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature review
BackgroundCavernous malformations are common vascular abnormalities of the central nervous system, but cavernous malformations of the cerebral aqueduct are rare. The choice of treatment is influenced by various factors.Case DescriptionWe report two cases of midbrain cavernous malformations. Both cas...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1513254/full |
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| author | Yibo Han Yibo Han Dong Liang Dong Liang Jing Guo Yibao Wang Yong Wang |
| author_facet | Yibo Han Yibo Han Dong Liang Dong Liang Jing Guo Yibao Wang Yong Wang |
| author_sort | Yibo Han |
| collection | DOAJ |
| description | BackgroundCavernous malformations are common vascular abnormalities of the central nervous system, but cavernous malformations of the cerebral aqueduct are rare. The choice of treatment is influenced by various factors.Case DescriptionWe report two cases of midbrain cavernous malformations. Both cases involved midbrain lesions obstructing the cerebral aqueduct, leading to obstructive hydrocephalus. The primary symptoms and complaints of the patients were related to hydrocephalus. Prior to surgery, patients underwent comprehensive imaging evaluations and received endoscopic third ventriculostomy rather than tumor resection. Both patients had favorable recoveries. We also reviewed the literature and discussed the choice of treatment strategies.ConclusionCavernous malformations are slow-progressing central nervous system lesions with a relatively benign natural course. When selecting a treatment strategy, clinicians should carefully consider the underlying cause of the patient’s primary symptoms and the specific objectives of the surgery. Avoiding overly aggressive resection that fails to address the main symptoms and potentially causes irreversible damage is crucial. |
| format | Article |
| id | doaj-art-0ba710a3532c42ae97144795191d9acc |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-0ba710a3532c42ae97144795191d9acc2025-01-28T06:41:32ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011510.3389/fonc.2025.15132541513254Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature reviewYibo Han0Yibo Han1Dong Liang2Dong Liang3Jing Guo4Yibao Wang5Yong Wang6Department of Neurosurgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, ChinaDepartment of Organ and Tissue Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, JapanDepartment of Neurosurgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, ChinaDepartment of Optical Neuroanatomy, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, JapanImaging technician in Charge, Shenyang Renren Kangye Hospital, Shenyang, Liaoning, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, ChinaBackgroundCavernous malformations are common vascular abnormalities of the central nervous system, but cavernous malformations of the cerebral aqueduct are rare. The choice of treatment is influenced by various factors.Case DescriptionWe report two cases of midbrain cavernous malformations. Both cases involved midbrain lesions obstructing the cerebral aqueduct, leading to obstructive hydrocephalus. The primary symptoms and complaints of the patients were related to hydrocephalus. Prior to surgery, patients underwent comprehensive imaging evaluations and received endoscopic third ventriculostomy rather than tumor resection. Both patients had favorable recoveries. We also reviewed the literature and discussed the choice of treatment strategies.ConclusionCavernous malformations are slow-progressing central nervous system lesions with a relatively benign natural course. When selecting a treatment strategy, clinicians should carefully consider the underlying cause of the patient’s primary symptoms and the specific objectives of the surgery. Avoiding overly aggressive resection that fails to address the main symptoms and potentially causes irreversible damage is crucial.https://www.frontiersin.org/articles/10.3389/fonc.2025.1513254/fullcavernous malformationsmidbrainhydrocephalusendoscopic third ventriculostomycase report |
| spellingShingle | Yibo Han Yibo Han Dong Liang Dong Liang Jing Guo Yibao Wang Yong Wang Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature review Frontiers in Oncology cavernous malformations midbrain hydrocephalus endoscopic third ventriculostomy case report |
| title | Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature review |
| title_full | Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature review |
| title_fullStr | Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature review |
| title_full_unstemmed | Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature review |
| title_short | Exploration of treatment strategies for cerebral cavernous malformations: two case reports on non-resection treatment and literature review |
| title_sort | exploration of treatment strategies for cerebral cavernous malformations two case reports on non resection treatment and literature review |
| topic | cavernous malformations midbrain hydrocephalus endoscopic third ventriculostomy case report |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1513254/full |
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