E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis

Introduction: Tobacco use is the leading cause of death in the U.S., and American Indian/Alaska Native people have high rates of tobacco-related diseases. Although the U.S. Food and Drug Administration–approved products and evidence-based methods exist for smoking cessation, people who smoke might u...

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Main Authors: Ashley L. Comiford, DrPH, Dorothy A. Rhoades, MD, MPH, Justin D. Dvorak, PhD, Kai Ding, PhD, Noah Collins, Alexandra L. Blair, Mark P. Doescher, MD, MSPH
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:AJPM Focus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2773065424001202
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author Ashley L. Comiford, DrPH
Dorothy A. Rhoades, MD, MPH
Justin D. Dvorak, PhD
Kai Ding, PhD
Noah Collins
Alexandra L. Blair
Mark P. Doescher, MD, MSPH
author_facet Ashley L. Comiford, DrPH
Dorothy A. Rhoades, MD, MPH
Justin D. Dvorak, PhD
Kai Ding, PhD
Noah Collins
Alexandra L. Blair
Mark P. Doescher, MD, MSPH
author_sort Ashley L. Comiford, DrPH
collection DOAJ
description Introduction: Tobacco use is the leading cause of death in the U.S., and American Indian/Alaska Native people have high rates of tobacco-related diseases. Although the U.S. Food and Drug Administration–approved products and evidence-based methods exist for smoking cessation, people who smoke might use E-cigarettes as cessation aids. Whether E-cigarette use is associated with the use of evidence-based methods is unknown, particularly among American Indian/Alaska Native individuals. Methods: Using survey data collected in 2016 from 289 adult American Indian people who smoke and who reported a previous cessation attempt, the authors conducted multivariate logistic regression analyses to assess the associations between E-cigarette use and evidence-based cessation methods. Analyses were performed in 2023. Results: Individuals who currently or formerly used E-cigarettes were significantly more likely to report using nicotine replacement therapy during their last quit attempt than those who did not use E-cigarettes (current versus never AOR=4.6, 95% CI=1.9, 11.9; past versus never AOR=4.6, 95% CI=2.2, 9.8; p<0.001). Current and former E-cigarette use was significantly associated with prescription use in the unadjusted analysis but lost significance in the adjusted analysis (current versus never AOR=3.1, 95% CI=1.0, 10.5; past versus never AOR=2.7, 95% CI=1.1, 7.9; p>0.05). Individuals with current or former use of E-cigarettes were significantly less likely than individuals who never used E-cigarettes to use the cold turkey method (unassisted cessation) (current versus never AOR=0.3, 95% CI=0.2, 0.6; past versus never AOR=0.3, 95% CI=0.1, 0.7; p<0.01). Conclusions: These results suggest that persons who use E-cigarettes are more likely than individuals who do not use E-cigarettes to previously have tried nicotine replacement therapy but less likely to use the cold turkey method. A larger study is needed to determine whether individuals who use E-cigarettes are also more likely to have tried prescription medication for smoking cessation. Whether E-cigarette use impedes or encourages the use of evidence-based cessation methods is unknown.
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spelling doaj-art-0ba36a9cdd254b83ba87f2903c5e9b8b2025-02-09T05:01:47ZengElsevierAJPM Focus2773-06542025-04-0142100302E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional AnalysisAshley L. Comiford, DrPH0Dorothy A. Rhoades, MD, MPH1Justin D. Dvorak, PhD2Kai Ding, PhD3Noah Collins4Alexandra L. Blair5Mark P. Doescher, MD, MSPH6Cherokee Nation Health Services, Cherokee Nation, Tahlequah, Oklahoma; Address correspondence to: Ashley L. Comiford, DrPH, Cherokee Nation Health Services, Cherokee Nation, 19600 East Ross Street, Tahlequah OK 74464.Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OklahomaDepartment of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OklahomaDepartment of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OklahomaPrinceton University, Princeton, New JerseyOklahoma State University, Stillwater, OklahomaStephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Department of Family and Preventive Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OklahomaIntroduction: Tobacco use is the leading cause of death in the U.S., and American Indian/Alaska Native people have high rates of tobacco-related diseases. Although the U.S. Food and Drug Administration–approved products and evidence-based methods exist for smoking cessation, people who smoke might use E-cigarettes as cessation aids. Whether E-cigarette use is associated with the use of evidence-based methods is unknown, particularly among American Indian/Alaska Native individuals. Methods: Using survey data collected in 2016 from 289 adult American Indian people who smoke and who reported a previous cessation attempt, the authors conducted multivariate logistic regression analyses to assess the associations between E-cigarette use and evidence-based cessation methods. Analyses were performed in 2023. Results: Individuals who currently or formerly used E-cigarettes were significantly more likely to report using nicotine replacement therapy during their last quit attempt than those who did not use E-cigarettes (current versus never AOR=4.6, 95% CI=1.9, 11.9; past versus never AOR=4.6, 95% CI=2.2, 9.8; p<0.001). Current and former E-cigarette use was significantly associated with prescription use in the unadjusted analysis but lost significance in the adjusted analysis (current versus never AOR=3.1, 95% CI=1.0, 10.5; past versus never AOR=2.7, 95% CI=1.1, 7.9; p>0.05). Individuals with current or former use of E-cigarettes were significantly less likely than individuals who never used E-cigarettes to use the cold turkey method (unassisted cessation) (current versus never AOR=0.3, 95% CI=0.2, 0.6; past versus never AOR=0.3, 95% CI=0.1, 0.7; p<0.01). Conclusions: These results suggest that persons who use E-cigarettes are more likely than individuals who do not use E-cigarettes to previously have tried nicotine replacement therapy but less likely to use the cold turkey method. A larger study is needed to determine whether individuals who use E-cigarettes are also more likely to have tried prescription medication for smoking cessation. Whether E-cigarette use impedes or encourages the use of evidence-based cessation methods is unknown.http://www.sciencedirect.com/science/article/pii/S2773065424001202American Indian/Alaska Nativesmoking cessationE-cigarettesevidence-based methods
spellingShingle Ashley L. Comiford, DrPH
Dorothy A. Rhoades, MD, MPH
Justin D. Dvorak, PhD
Kai Ding, PhD
Noah Collins
Alexandra L. Blair
Mark P. Doescher, MD, MSPH
E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis
AJPM Focus
American Indian/Alaska Native
smoking cessation
E-cigarettes
evidence-based methods
title E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis
title_full E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis
title_fullStr E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis
title_full_unstemmed E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis
title_short E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis
title_sort e cigarette use and use of evidence based smoking cessation methods among american indian cigarette smokers a cross sectional analysis
topic American Indian/Alaska Native
smoking cessation
E-cigarettes
evidence-based methods
url http://www.sciencedirect.com/science/article/pii/S2773065424001202
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