Htra4 promotes vascular endothelial cell injury and is associated with the early-onset of preeclampsia

Htra4 promotes vascular endothelial cell injury and is associated with the early-onset of preeclampsia

Abstract Preeclampsia (PE) is a pregnancy-specific disorder characterized by multi-system involvement, leading to increased perinatal morbidity and mortality as well as long-term cardiovascular damage in both mother and fetus. This study aimed to investigate the alterations and potential role of hig...

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Bibliographic Details
Main Authors: Hongfang Kong, Xuyuan Ma, Fang Wang, Yuan Su, Yaqing Chang, Hong Xin
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Early-onset PE
Htra4
Adverse outcomes
Vascular endothelial injury
Online Access:https://doi.org/10.1038/s41598-025-96819-5
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