A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function

A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function

Chronic kidney disease (CKD) is characterized by accumulation of uremic toxins (UTs), such as p-cresyl sulfate and indoxyl sulfate, generated through the transformation of tyrosine and tryptophan by the gut microbiota. Using an ex vivo Simulator of the Human Intestinal Microbial Ecosystem (SHIME) co...

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Bibliographic Details
Main Authors: Alice Beau, Jane Natividad, Berengère Benoit, Philippe Delerive, Stéphane Duboux, Yuan Feng, Marie Jammes, Cecile Barnel, Giuseppina Sequino, Claudie Pinteur, Griet Glorieux, Denis Fouque, Hubert Vidal, Laetitia Koppe
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Multi-biotic
chronic kidney disease
uremic toxins
gut microbiota
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2531202
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