β-Cell Generation: Can Rodent Studies Be Translated to Humans?

β-cell replacement by allogeneic islet transplantation is a promising approach for patients with type 1 diabetes, but the shortage of organ donors requires new sources of β cells. Islet regeneration in vivo and generation of β-cells ex vivo followed by transplantation represent attractive therapeuti...

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Bibliographic Details
Main Authors: Françoise Carlotti, Arnaud Zaldumbide, Johanne H. Ellenbroek, H. Siebe Spijker, Rob C. Hoeben, Eelco J. de Koning
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2011/892453
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