Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.

<h4>Background</h4>Surgical site infections (SSIs) are a major yet preventable cause of poor post-operative clinical outcomes, prolonged ICU/hospital stay, increased antibiotic consumption and added cost of therapy. Low- and Middle-income Countries (LMICs) have disproportionately higher...

Full description

Saved in:
Bibliographic Details
Main Authors: Rachna Rohilla, Mayank Gupta, Thekkumkara Surendran Anish, Jerin Jose Cherian, Mahendra Pratap Singh, Ashish Kumar Kakkar, Aparna Mukherjee, Niti Mittal, Sandeep Kaushal, Devi Vijay, Robin Kaushik, Syed Shariq Naeem, Jaykaran Charan, IMPRESS (‘Impact of Multi-Pronged intervention on REducing Surgical Site Infection’) Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319645
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850162997750661120
author Rachna Rohilla
Mayank Gupta
Thekkumkara Surendran Anish
Jerin Jose Cherian
Mahendra Pratap Singh
Ashish Kumar Kakkar
Aparna Mukherjee
Niti Mittal
Sandeep Kaushal
Devi Vijay
Robin Kaushik
Syed Shariq Naeem
Jaykaran Charan
IMPRESS (‘Impact of Multi-Pronged intervention on REducing Surgical Site Infection’) Study Group
author_facet Rachna Rohilla
Mayank Gupta
Thekkumkara Surendran Anish
Jerin Jose Cherian
Mahendra Pratap Singh
Ashish Kumar Kakkar
Aparna Mukherjee
Niti Mittal
Sandeep Kaushal
Devi Vijay
Robin Kaushik
Syed Shariq Naeem
Jaykaran Charan
IMPRESS (‘Impact of Multi-Pronged intervention on REducing Surgical Site Infection’) Study Group
author_sort Rachna Rohilla
collection DOAJ
description <h4>Background</h4>Surgical site infections (SSIs) are a major yet preventable cause of poor post-operative clinical outcomes, prolonged ICU/hospital stay, increased antibiotic consumption and added cost of therapy. Low- and Middle-income Countries (LMICs) have disproportionately higher rates of SSIs as compared to high-income countries despite various national and international guidelines in place as multipronged, combined interventions are seldom used. The IMPRESS project aims to respond to this urgent need to identify and evaluate the quality improvement measures contextualized to the logistic constraints of LMIC settings such as India.<h4>Methods and analysis</h4>We adopt a multi-center longitudinal mixed-methods study to be conducted over a period of 2 years in various phases. Phase 1 will be formative research with the objective of identifying knowledge gaps and baseline data collection. Phase II will involve co-development of multipronged interventions addressing identified barriers. Phase III will focus on the deployment of the selected multipronged interventions. Phase IV will be the post-intervention phase to evaluate the impact of the interventions. The study has been prospectively registered with CTRI and is supported by a funding grant from the Indian Council of Medical Research, New Delhi. The Institutional Ethics Committee approval has been obtained from all the sites involved in the study.
format Article
id doaj-art-0b8f96b1440e4cba9f41b8f46a2e6be4
institution OA Journals
issn 1932-6203
language English
publishDate 2025-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj-art-0b8f96b1440e4cba9f41b8f46a2e6be42025-08-20T02:22:25ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01203e031964510.1371/journal.pone.0319645Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.Rachna RohillaMayank GuptaThekkumkara Surendran AnishJerin Jose CherianMahendra Pratap SinghAshish Kumar KakkarAparna MukherjeeNiti MittalSandeep KaushalDevi VijayRobin KaushikSyed Shariq NaeemJaykaran CharanIMPRESS (‘Impact of Multi-Pronged intervention on REducing Surgical Site Infection’) Study Group<h4>Background</h4>Surgical site infections (SSIs) are a major yet preventable cause of poor post-operative clinical outcomes, prolonged ICU/hospital stay, increased antibiotic consumption and added cost of therapy. Low- and Middle-income Countries (LMICs) have disproportionately higher rates of SSIs as compared to high-income countries despite various national and international guidelines in place as multipronged, combined interventions are seldom used. The IMPRESS project aims to respond to this urgent need to identify and evaluate the quality improvement measures contextualized to the logistic constraints of LMIC settings such as India.<h4>Methods and analysis</h4>We adopt a multi-center longitudinal mixed-methods study to be conducted over a period of 2 years in various phases. Phase 1 will be formative research with the objective of identifying knowledge gaps and baseline data collection. Phase II will involve co-development of multipronged interventions addressing identified barriers. Phase III will focus on the deployment of the selected multipronged interventions. Phase IV will be the post-intervention phase to evaluate the impact of the interventions. The study has been prospectively registered with CTRI and is supported by a funding grant from the Indian Council of Medical Research, New Delhi. The Institutional Ethics Committee approval has been obtained from all the sites involved in the study.https://doi.org/10.1371/journal.pone.0319645
spellingShingle Rachna Rohilla
Mayank Gupta
Thekkumkara Surendran Anish
Jerin Jose Cherian
Mahendra Pratap Singh
Ashish Kumar Kakkar
Aparna Mukherjee
Niti Mittal
Sandeep Kaushal
Devi Vijay
Robin Kaushik
Syed Shariq Naeem
Jaykaran Charan
IMPRESS (‘Impact of Multi-Pronged intervention on REducing Surgical Site Infection’) Study Group
Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.
PLoS ONE
title Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.
title_full Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.
title_fullStr Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.
title_full_unstemmed Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.
title_short Multipronged interventions to reduce surgical site infections: A multicenter implementation research protocol.
title_sort multipronged interventions to reduce surgical site infections a multicenter implementation research protocol
url https://doi.org/10.1371/journal.pone.0319645
work_keys_str_mv AT rachnarohilla multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT mayankgupta multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT thekkumkarasurendrananish multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT jerinjosecherian multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT mahendrapratapsingh multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT ashishkumarkakkar multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT aparnamukherjee multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT nitimittal multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT sandeepkaushal multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT devivijay multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT robinkaushik multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT syedshariqnaeem multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT jaykarancharan multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol
AT impressimpactofmultiprongedinterventiononreducingsurgicalsiteinfectionstudygroup multiprongedinterventionstoreducesurgicalsiteinfectionsamulticenterimplementationresearchprotocol