A comparative parasitological, histopathological, and proteomic analysis of Schistosoma mansoni infected mice treated with ivermectin and praziquantel

A comparative parasitological, histopathological, and proteomic analysis of Schistosoma mansoni infected mice treated with ivermectin and praziquantel

This study was designed to compare the effectiveness of ivermectin (IVM) with praziquantel (PZQ) in treating Schistosoma mansoni-infected mice through biological and proteomic analysis. Detecting protein structure changes in the worms after treatment could help pursue drug efficacy in schistosomiasi...

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Bibliographic Details
Main Authors: Eman Sayed El-Wakil, Mona Mohamed Tolba, Mona Hasan El-Sayad, Maha Khairy Hassen, Hayat S. Al-Rashidi, Mina A. Almayouf, Wafa Abdullah I. Al-Megrin, Hind Alzaylaee, Esraa Abdelhamid Moneer
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Veterinary Science
Subjects:
ivermectin
praziquantel
proteomic analysis
scanning electron microscope
Schistosoma mansoni
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1646155/full
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