Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection

Before initiating Yttrium-90 (90Y) radioembolization, both the interventional radiology and nuclear medicine departments must prepare facilities for radionuclide handling, implement appropriate radiation protection and monitoring measures, and ensure that all medical personnel possess the require...

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Main Author: Dongho Hyun
Format: Article
Language:English
Published: The Korean Society of Radiology 2025-07-01
Series:Journal of the Korean Society of Radiology
Subjects:
Online Access:https://doi.org/10.3348/jksr.2025.0049
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author Dongho Hyun
author_facet Dongho Hyun
author_sort Dongho Hyun
collection DOAJ
description Before initiating Yttrium-90 (90Y) radioembolization, both the interventional radiology and nuclear medicine departments must prepare facilities for radionuclide handling, implement appropriate radiation protection and monitoring measures, and ensure that all medical personnel possess the required government-issued certification. According to current guidelines, transarterial radioembolization is recommended as an alternative treatment option for patients with a single hepatocellular carcinoma measuring ≤8 cm and classified as stage I, II, or III according to the modified Union for International Cancer Control staging system. However, these indications may be adjusted based on the institution’s medical clinical setting and resources. Given the potential for irreversible tissue damage from 90Y, treatment efficacy and safety must be assessed through planning angiography and either planar imaging or SPECT-CT using 99mTc-macroaggregated albumin.
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spelling doaj-art-0b79e310e8204e2f82623a40369d21082025-08-20T03:08:48ZengThe Korean Society of RadiologyJournal of the Korean Society of Radiology2951-08052025-07-01864447456https://doi.org/10.3348/jksr.2025.0049Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient SelectionDongho HyunBefore initiating Yttrium-90 (90Y) radioembolization, both the interventional radiology and nuclear medicine departments must prepare facilities for radionuclide handling, implement appropriate radiation protection and monitoring measures, and ensure that all medical personnel possess the required government-issued certification. According to current guidelines, transarterial radioembolization is recommended as an alternative treatment option for patients with a single hepatocellular carcinoma measuring ≤8 cm and classified as stage I, II, or III according to the modified Union for International Cancer Control staging system. However, these indications may be adjusted based on the institution’s medical clinical setting and resources. Given the potential for irreversible tissue damage from 90Y, treatment efficacy and safety must be assessed through planning angiography and either planar imaging or SPECT-CT using 99mTc-macroaggregated albumin.https://doi.org/10.3348/jksr.2025.0049radioembolizationplanning angiography99mtc-maascintigraphyhepatocellular carcinoma
spellingShingle Dongho Hyun
Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection
Journal of the Korean Society of Radiology
radioembolization
planning angiography
99mtc-maa
scintigraphy
hepatocellular carcinoma
title Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection
title_full Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection
title_fullStr Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection
title_full_unstemmed Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection
title_short Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection
title_sort transarterial radioembolization for hepatocellular carcinoma in korea current clinical practices facility requirements and patient selection
topic radioembolization
planning angiography
99mtc-maa
scintigraphy
hepatocellular carcinoma
url https://doi.org/10.3348/jksr.2025.0049
work_keys_str_mv AT donghohyun transarterialradioembolizationforhepatocellularcarcinomainkoreacurrentclinicalpracticesfacilityrequirementsandpatientselection