Transcription factor SP4 is a susceptibility gene for bipolar disorder.

Transcription factor SP4 is a susceptibility gene for bipolar disorder.

The Sp4 transcription factor plays a critical role for both development and function of mouse hippocampus. Reduced expression of the mouse Sp4 gene results in a variety of behavioral abnormalities relevant to human psychiatric disorders. The human SP4 gene is therefore examined for its association w...

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Bibliographic Details
Main Authors: Xianjin Zhou, Wei Tang, Tiffany A Greenwood, Shengzhen Guo, Lin He, Mark A Geyer, John R Kelsoe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005196&type=printable
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