Exploring the link between M1 macrophages and EMT of amniotic epithelial cells: implications for premature rupture of membranes

Exploring the link between M1 macrophages and EMT of amniotic epithelial cells: implications for premature rupture of membranes

Abstract Background Despite increasing evidence supporting the role of an amniotic epithelial-mesenchymal transition (EMT) in the premature rupture of membranes (PROMs), it remains unclear if extracellular vesicle (EV) derived from M1 macrophages play a critical role in triggering the EMT of amnioti...

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Bibliographic Details
Main Authors: Yuhua Gao, Yanan Zhang, Ningning Mi, Wang Miao, Jingmiao Zhang, Yize Liu, Zhikun Li, Jiaxun Song, Xiangchen Li, Weijun Guan, Chunyu Bai
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Nanobiotechnology
Subjects:
Amniotic epithelial cells
Extracellular vesicles
Macrophages
Epithelial-mesenchymal transition
Online Access:https://doi.org/10.1186/s12951-025-03192-6
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